Boonsiri Metavee, Marks Katherine C, Ditre Chérie M
Cosmetic Enhancement Center, Penn Medicine in Radnor, University of Pennsylvania, Radnor, Pennsylvania.
J Clin Aesthet Dermatol. 2016 Mar;9(3):48-50. Epub 2016 Mar 1.
Practitioners are increasingly using topical anesthetics in the field of dermatology. Application of topical anesthetics prior to performing dermatologic procedures has proven to decrease pain and discomfort associated with these procedures. Despite the prevalent use of topical anesthetics, there are few standard guidelines for about which products provide optimal and safest use. Adverse events are often correlated with improper application of topical anesthetics. A few case reports have cited adverse events related to the use of compounded products that the United States Food and Drug Administration has not approved, such as benzocaine, lidocaine, tetracaine. In this article, the authors report the possible ocular side effects due to the use of benzocaine, lidocaine, tetracaine. Careful attention must be paid to this compounded product, and better formulations are needed in order to prevent adverse events.
皮肤科医生越来越多地在皮肤病学领域使用局部麻醉剂。在进行皮肤科手术前使用局部麻醉剂已被证明可以减轻与这些手术相关的疼痛和不适。尽管局部麻醉剂使用普遍，但关于哪些产品能提供最佳和最安全使用的标准指南却很少。不良事件往往与局部麻醉剂的不当使用有关。一些病例报告提到了与使用美国食品药品监督管理局未批准的复方产品（如苯佐卡因、利多卡因、丁卡因）相关的不良事件。在本文中，作者报告了使用苯佐卡因、利多卡因、丁卡因可能导致的眼部副作用。必须密切关注这种复方产品，并且需要更好的配方以预防不良事件。
