Pančevová Pavla, Vodička Martin, Vašut Karel, Forejtar Milan
Ceska Slov Farm. 2016 Spring;65(2):78-81.
Constipation is a disease which increases in the senior population and is a common complication for hospitalised patients. Among the risk factors are age, female gender, immobility, diet, fluid intake and polypharmacotherapy. The aim of the study was to analyse the prevalence of constipation according to the used drugs and known risk factors in a population with a high prevalence of constipation. In the department of clinical gerontology, observational prevalence point study was performed using a questionnaire involving 100 patients based on the patients subjective perception of constipation. Prevalence of constipation was determined according to the drug categories and individual drugs, gender, age, mobility, diagnosis, diet and fluid intake. There were 59 patients who suffered from constipation. A high prevalence of constipation was associated with the diet, the principal diagnosis, and mainly the use of drugs. Among the drugs associated with constipation were the calcium channel blockers of 21 patients out of 28, HMG-CoA reductase inhibitors of 22 patients out of 30, drugs for the treatment of increased urinary frequency and incontinence of 6 patients out of 6 and bisoprolol of 10 patients out of 11. Hospitalisation of seniors is connected with the high prevalence of constipation that is increased by the use of drugs that influence constipation. A change in the therapeutic value of drugs should be taken into consideration during the pharmacotherapy of this group of patients.
constipation risks factors for constipation drug-induced constipation.
便秘是一种在老年人群中发病率上升的疾病，也是住院患者常见的并发症。其风险因素包括年龄、女性性别、活动不便、饮食、液体摄入量和多种药物治疗。本研究的目的是根据所用药物和已知风险因素，分析便秘高发人群中便秘的患病率。在临床老年病科，采用问卷调查法对100例患者进行观察性患病率定点研究，该问卷基于患者对便秘的主观感受。根据药物类别和个别药物、性别、年龄、活动能力、诊断、饮食和液体摄入量来确定便秘的患病率。有59例患者患有便秘。便秘的高患病率与饮食、主要诊断以及主要与药物的使用有关。与便秘相关的药物包括28例患者中的21例使用的钙通道阻滞剂、30例患者中的22例使用的HMG-CoA还原酶抑制剂、6例患者中的6例使用的治疗尿频和尿失禁的药物以及11例患者中的10例使用的比索洛尔。老年人住院与便秘的高患病率有关，而使用影响便秘的药物会使患病率增加。在对这组患者进行药物治疗时，应考虑药物治疗价值的变化。
便秘；便秘的风险因素；药物性便秘
