可卡因与酒精联合给药对小鼠的刺激作用增强。
Increased stimulatory effect by the combined administration of cocaine and alcohol in mice.
作者信息
Masur J, Souza-Formigoni M L, Pires M L
机构信息
Department of Psicobiologia, Escola Paulista de Medicina, São Paulo, Brazil.
出版信息
Alcohol. 1989 May-Jun;6(3):181-2. doi: 10.1016/0741-8329(89)90015-3.
PMID:2736076
Abstract
Locomotor activity was recorded after 5-30 mg/kg of cocaine in mice pretreated or not with a stimulant dose of ethanol (2.0 g/kg). The increase in locomotion induced by the association of cocaine plus ethanol was significantly larger when compared to either the group injected with only cocaine or only ethanol.
摘要
在给予或未给予兴奋剂量乙醇（2.0 g/kg）预处理的小鼠中，记录给予5 - 30 mg/kg可卡因后的自发活动。与单独注射可卡因或单独注射乙醇的组相比，可卡因加乙醇联合注射引起的活动增加显著更大。
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