Centre for Children's Health Research, Queensland University of Technology, Brisbane, QLD
Respiratory and Sleep Medicine, Lady Cilento Children's Hospital, Brisbane, QLD.
Med J Aust. 2016 Jul 4;205(1):35-40. doi: 10.5694/mja16.00226.
To evaluate published spirometry data for Australian Aboriginal and Torres Strait Islander (Indigenous) peoples to determine (i) whether their ethnicity influenced spirometry results; and (ii) if any reliable spirometry reference values exist for Indigenous Australians.
Systematic review of published and grey literature.
PubMed and Cochrane Library databases, references of included articles and appropriate grey literature. Last searches were conducted in April 2016.
We included any study that performed spirometry on healthy Indigenous Australians and compared their results with those from people of European ancestry. Two authors independently screened titles and abstracts and then reviewed potentially relevant full-text articles for possible inclusion. We used PRISMA systematic review reporting methods to collate data.
Of a possible 125 studies, 18 full-text articles were reviewed, but only nine fulfilled the inclusion criteria. None specified Torres Strait Islander inclusion. All studies reported lower spirometry values (as much as 30% lower) for Aboriginal people compared with non-Indigenous people. Five studies developed spirometry reference values for Indigenous Australians; however, none adhered to all participant inclusion and exclusion criteria outlined by the American Thoracic Society and European Respiratory Society. Hence, reported results and subsequent reference values may not be a true representation of spirometry values in healthy Indigenous people.
The lower spirometry values reported for Indigenous Australians may be due to study limitations. Furthermore, there are currently no reliable spirometry reference values for Indigenous Australians that adhere to current guidelines. Developing a set of Indigenous Australian reference values will improve the accuracy of test interpretation and aid in the diagnosis of respiratory disease in this population.
评估已发表的澳大利亚原住民和托雷斯海峡岛民（土著）人群的肺活量测定数据，以确定：（i）他们的种族是否影响肺活量测定结果；以及（ii）是否存在适用于澳大利亚土著人的可靠肺活量测定参考值。
已发表和灰色文献的系统评价。
PubMed 和 Cochrane 图书馆数据库、纳入文章的参考文献和适当的灰色文献。最后一次搜索是在 2016 年 4 月进行的。
我们纳入了对健康澳大利亚土著人进行肺活量测定并将其结果与欧洲血统人群进行比较的任何研究。两位作者独立筛选标题和摘要，然后审查潜在相关的全文文章以确定是否纳入。我们使用 PRISMA 系统评价报告方法来整理数据。
在可能的 125 项研究中，有 18 篇全文文章进行了审查，但只有 9 篇符合纳入标准。没有研究明确包括托雷斯海峡岛民。所有研究都报告说，与非土著人相比，原住民的肺活量测定值较低（低达 30%）。五项研究为澳大利亚土著人制定了肺活量测定参考值；然而，没有一项研究符合美国胸科学会和欧洲呼吸学会规定的所有参与者纳入和排除标准。因此，报告的结果和随后的参考值可能无法真实反映健康土著人的肺活量测定值。
报告的澳大利亚原住民肺活量较低可能是由于研究限制所致。此外，目前没有适用于澳大利亚土著人的可靠肺活量测定参考值，这些参考值符合现行指南。制定一套澳大利亚土著人的参考值将提高测试解释的准确性，并有助于在该人群中诊断呼吸疾病。
