Totten Crystal F, Davenport Daniel L, Ward Nicholas D, Roth J Scott
Department of Surgery, University of Kentucky, Lexington, Kentucky.
Department of Surgery, University of Kentucky, Lexington, Kentucky.
J Surg Res. 2016 Jun 15;203(2):459-65. doi: 10.1016/j.jss.2016.02.040. Epub 2016 Mar 4.
Patients undergoing ventral hernia repair (VHR) with biologic mesh (BioM) have higher hospital costs compared with synthetic mesh (SynM). This study compares 90-d pre- and post-VHR hospital costs (180-d) among BioM and SynM based on infection risk.
This retrospective National Surgical Quality Improvement Program study matched patient perioperative risk with resource utilization cost for a consecutive series of VHR repairs. Patient infection risks, clinical and financial outcomes were compared in unmatched SynM (n = 303) and BioM (n = 72) groups. Propensity scores were used to match 35 SynM and BioM pairs of cases with similar infection risk for outcomes analysis.
BioM patients in the unmatched group were older with higher American Society of Anesthesiologists (ASA) and wound classification, and they more frequently underwent open repairs for recurrent hernias. Wound surgical site infections were more frequent in unmatched BioM patients (P = 0.001) as were 180-d costs ($43.8k versus $14.0k, P < 0.001). Propensity matching resulted in 31 clean cases. In these low-risk patients, wound occurrences and readmissions were identical, but 180-d costs remained higher ($31.8k versus $15.5k, P < 0.001). There were no differences in hospital 180-d diagnostic, emergency room, intensive care unit, floor, pharmacy, or therapeutic costs. However, 180-d operating room services and supply costs were higher in the BioM group ($21.1k versus $7.1k, P < 0.001).
BioM is used more commonly in hernia repairs involving higher wound class and ASA scores and recurrent hernias. Clinical outcomes after low-risk VHRs are similar; SynM utilization in low-risk hernia repairs was more cost-effective.
与使用合成补片(SynM)相比,接受生物补片(BioM)腹疝修补术(VHR)的患者住院费用更高。本研究基于感染风险比较了BioM和SynM在VHR术前90天和术后(180天)的住院费用。
这项回顾性国家外科质量改进计划研究将患者围手术期风险与一系列连续VHR修复的资源利用成本进行匹配。在未匹配的SynM组(n = 303)和BioM组(n = 72)中比较患者感染风险、临床和财务结果。使用倾向评分匹配35对具有相似感染风险的SynM和BioM病例对进行结果分析。
未匹配组中的BioM患者年龄较大,美国麻醉医师协会(ASA)评分和伤口分类较高,并且他们更频繁地接受复发性疝的开放修补术。未匹配的BioM患者伤口手术部位感染更频繁(P = 0.001),180天费用也是如此(43800美元对14000美元,P < 0.001)。倾向匹配产生了31例清洁病例。在这些低风险患者中,伤口发生率和再入院率相同,但180天费用仍然更高(31800美元对15500美元,P < 0.001)。180天的医院诊断、急诊室、重症监护病房、病房、药房或治疗费用没有差异。然而,BioM组的180天手术室服务和供应成本更高(21100美元对7100美元,P < 0.001)。
BioM更常用于涉及较高伤口分级和ASA评分以及复发性疝的疝修补术。低风险VHR后的临床结果相似;在低风险疝修补术中使用SynM更具成本效益。