采用辅助性脂质救援和血浆置换治疗三环类抗抑郁药过量。
Tricyclic antidepressant overdose treated with adjunctive lipid rescue and plasmapheresis.
作者信息
Odigwe Chibuzo Clement, Tariq Madiha, Kotecha Tulsi, Mustafa Usman, Senussi Nizar, Ikwu Isaac, Bhattarcharya Anirban, Ngene John Ifeanyi, Ojiako Kizito, Iroegbu Nkemakolam
机构信息
Department of Medicine, St. Joseph Hospital, Chicago, Illinois.
出版信息
Proc (Bayl Univ Med Cent). 2016 Jul;29(3):284-7. doi: 10.1080/08998280.2016.11929437.
Abstract
Tricyclic antidepressant poisoning remains a major cause of morbidity and mortality, particularly in the setting of suicidal attempts. The current standard of care for treatment is the administration of sodium bicarbonate infusion. Adjunctive lipid emulsion therapy and plasmapheresis have received attention recently. We report an 18-year-old patient who was successfully managed with lipid emulsion and plasmapheresis as adjuncts to sodium bicarbonate treatment and review some of the recent literature.
摘要
三环类抗抑郁药中毒仍然是发病和死亡的主要原因，尤其是在自杀未遂的情况下。目前的治疗标准是输注碳酸氢钠。辅助性脂质乳剂疗法和血浆置换最近受到了关注。我们报告了一名18岁的患者，他通过脂质乳剂和血浆置换作为碳酸氢钠治疗的辅助手段成功得到了救治，并回顾了一些近期的文献。
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