Gupta Devanand, Gupta Rajendra Kumar, Jain Ankita, Bindhumadhav Suresh, Garg Purnima, Chaturvedi Saurabh, Chattu Vijay Kumar
Department of Public Health Dentistry, Institute of Dental Science, Bareilly, Uttar Pradesh, and General Secretory, International Society for Holistic Dentistry, India.
Principal, Government Degree College, Banbasa, Uttrakhand, India.
Pharmacognosy Res. 2016 Jul-Sep;8(3):169-72. doi: 10.4103/0974-8490.181456.
To evaluate the efficacy of Barleria prionitis extract mouthwash in comparison with gold standard chlorhexidine (CHX) mouthwash on the oral health.
A total of 30 subjects were randomly divided into two groups, B. prionitis group and the CHX gluconate mouthwash group. The data were collected at the baseline and 3 days. The plaque was disclosed using erythrosine disclosing agent and their scores were recorded using the Quigley and Hein plaque index modified by Turesky-Gilmore-Glickman. Statistical analysis was performed to compare the effect of the two drug regime.
Our result showed that the CHX and the B. prionitis were statistically equally effective against dental plaque. Although the action of CHX was more pronounced.
This study has confirmed antimicrobial potential of the plant B. prionitis, thus supporting its folklore application as preventive remedy against oral microbial diseases.
Within the limitation of this trial, herbal mouthwash has been shown to demonstrate similar effects on plaque as compared to the standard drug CHX. Further long term research needs to be done to check the efficacy and effectiveness of herbal products over standard drug regime.
评估刺山柑提取物漱口水与金标准洗必泰（CHX）漱口水相比对口腔健康的疗效。
总共30名受试者被随机分为两组，刺山柑组和葡萄糖酸洗必泰漱口水组。在基线和3天时收集数据。使用赤藓红显色剂使牙菌斑显色，并使用经图尔斯基 - 吉尔摩 - 利克曼修改的奎格利和海因菌斑指数记录其分数。进行统计分析以比较两种药物方案的效果。
我们的结果表明，CHX和刺山柑在对抗牙菌斑方面在统计学上具有同等效果。尽管CHX的作用更显著。
本研究证实了刺山柑这种植物的抗菌潜力，从而支持了其作为预防口腔微生物疾病的民间疗法的应用。
在本试验的局限性范围内，草药漱口水已被证明与标准药物CHX相比对牙菌斑有相似的效果。需要进一步进行长期研究以检查草药产品相对于标准药物方案的疗效和有效性。
