Tomii Masato, Mizuno Junichi, Watanabe Kazuo
Department of Neurosurgery, Southern TOHOKU General Hospital, Iwanuma, Miyagi, Japan.
Department of Neurosurgery, Southern TOHOKU General Hospital, Iwanuma, Miyagi, Japan; Department of Neurosurgery, Southern TOHOKU Research Institute for Neuroscience, Southern TOHOKU General Hospital, Koriyama, Fukushima, Japan.
Asian J Neurosurg. 2016 Jul-Sep;11(3):273-5. doi: 10.4103/1793-5482.175624.
The purpose of this study was to elucidate the pathological characteristics of C3-C4 cervical spondylotic myelopathy (CSM) from the radiological study.
A total of 31 patients with single level anterior cervical discectomy and fusion (ACDF) at C3-C4 and 46 patients with single level ACDF at C5-C6 were included in this study. We selected C5-C6 level as a representative of the lower cervical level. The C3-C4 and C5-C6 levels were routinely examined to investigate the areas of the vertebral canal, subarachnoid space, and spinal cord in the cervical canal.
The clinical study of C3-C4 ACDF patients showed that as for the C3-C4 area, the area of the cervical vertebral canal, the area of the subarachnoid space, and he transverse surface area of the spinal cord were all significantly smaller in C3-C4 ACDF patients than in C5-C6 ACDF patients. Moreover, as for the C5-C6 area, only the area of the subarachnoid space was significantly smaller in C5-C6 ACDF patients than in C3-C4 ACDF patients. Spondylotic changes predominated at both the C3-C4 and C5-C6 levels. However, in the C5-C6 ACDF patients, spondylotic changes tended to predominate only at the operation level at C5-C6.
Aging process develops from lower cervical to upper cervical level. Moreover, this static factor in conjunction with dynamic factor (instability) was the causative factors for the CSM in C3-C4 ACDF patients.
本研究旨在通过影像学研究阐明C3 - C4节段脊髓型颈椎病(CSM)的病理特征。
本研究纳入了31例行C3 - C4单节段颈椎前路椎间盘切除融合术(ACDF)的患者和46例行C5 - C6单节段ACDF的患者。我们选择C5 - C6节段作为下颈椎节段的代表。对C3 - C4和C5 - C6节段进行常规检查,以研究颈椎管、蛛网膜下腔和颈段脊髓的区域。
C3 - C4 ACDF患者的临床研究表明,对于C3 - C4区域,C3 - C4 ACDF患者的颈椎管面积、蛛网膜下腔面积和脊髓横截面积均显著小于C5 - C6 ACDF患者。此外,对于C5 - C6区域,C5 - C6 ACDF患者仅蛛网膜下腔面积显著小于C3 - C4 ACDF患者。C3 - C4和C5 - C6节段均以骨质增生性改变为主。然而,在C5 - C6 ACDF患者中,骨质增生性改变仅倾向于在C5 - C6手术节段为主。
衰老过程从下颈椎向上颈椎发展。此外,这种静态因素与动态因素(不稳定)是C3 - C4 ACDF患者发生CSM的致病因素。