Saxena Shailendra K, Elahi Asif, Gadugu Srinivasulu, Prasad Anil K
CSIR-Centre for Cellular and Molecular Biology (CCMB), Uppal Road, Hyderabad, TS 500007 India.
Virusdisease. 2016 Jun;27(2):111-5. doi: 10.1007/s13337-016-0307-y. Epub 2016 Feb 20.
Zika virus (ZIKV) infection is a new emerging threat around the globe which might be responsible for microcephaly and Guillain-Barre syndrome in the infants. Recently, ZIKV outbreak has caused a public health crisis in Brazil after being linked to a sharp increase in birth defects. ZIKV is ssRNA virus belongs to the family Flaviviridae. It is mainly transmitted by mosquito bite specifically Aedes species and disease symptoms include fever, joint pain, muscle pain, rash, conjunctivitis, and headache. The reservoir of ZIKV is still not known. Protection at personal level by avoiding mosquito bite would help to reduce the incidence of the disease. Control of ZIKV infection by vaccination or antiviral drug either from modern, complementary and alternative medicines may be considered to be one of the most effective strategies in the long run. Large scale immunization of susceptible human population is highly required to prevent this deadly disease. Attempts should be made as soon as possible to develop effective vaccines or antiviral to prevent ZIKV infection. This article provides a current overview of the experimental therapeutics and treatment options based on modern, complementary and alternative medicines.
寨卡病毒（ZIKV）感染是全球新出现的一种威胁，可能导致婴儿患小头畸形和吉兰-巴雷综合征。最近，寨卡病毒疫情在巴西引发了一场公共卫生危机，此前它与出生缺陷的急剧增加有关。寨卡病毒是一种单链RNA病毒，属于黄病毒科。它主要通过蚊虫叮咬传播，特别是伊蚊属，疾病症状包括发热、关节疼痛、肌肉疼痛、皮疹、结膜炎和头痛。寨卡病毒的宿主仍不清楚。通过避免蚊虫叮咬在个人层面进行防护有助于降低该病的发病率。从长远来看，通过接种疫苗或使用来自现代医学、补充医学和替代医学的抗病毒药物来控制寨卡病毒感染，可能被认为是最有效的策略之一。迫切需要对易感人群进行大规模免疫接种以预防这种致命疾病。应尽快尝试研发有效的疫苗或抗病毒药物来预防寨卡病毒感染。本文概述了基于现代医学、补充医学和替代医学的实验性治疗方法和治疗选择。
