Nielsen Suzanne, Menon Nadia, Larney Sarah, Farrell Michael, Degenhardt Louisa
National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia.
Drug and Alcohol Services, South Eastern Sydney Local Health District, Surry Hills, NSW, Australia.
Addiction. 2016 Dec;111(12):2177-2186. doi: 10.1111/add.13517. Epub 2016 Aug 16.
Given the potential to expand naloxone supply through community pharmacy, the aim of this study was to estimate Australian pharmacists': (1) level of support for overdose prevention, (2) barriers and facilitators for naloxone supply and (3) knowledge about naloxone administration.
Online survey from nationally representative sample of community pharmacies.
Australia, September-November 2015.
A total of 1317 community pharmacists were invited to participate with 595 responses (45.1%).
We assessed attitudes towards harm reduction, support for overdose prevention, attitudes and knowledge about naloxone. We tested the association between attitudes towards harm reduction and different aspects of naloxone supply.
Pharmacists were willing to receive training about naloxone (n = 479, 80.5%) and provide naloxone with a prescription (n = 537, 90.3%). Fewer (n = 234, 40.8%) were willing to supply naloxone over-the-counter. Positive attitudes towards harm reduction were associated with greater willingness to supply naloxone with a prescription [odds ratio (OR) = 1.15, 95% confidence interval (CI) = 1.11-1.19] and over-the-counter (OR = 1.13, 95% CI = 1.09-1.17). Few pharmacists were confident they could identify appropriate patients (n = 203, 34.1%) and educate them on overdose and naloxone use (n = 190, 31.9%). Mean naloxone knowledge scores were 1.8 (standard deviation 1.7) out of 5. More than half the sample identified lack of time, training, knowledge and reimbursement as potential barriers for naloxone provision.
Community pharmacists in Australia appear to be willing to supply naloxone. Low levels of knowledge about naloxone pharmacology and administration highlight the importance of training pharmacists about overdose prevention.
鉴于通过社区药房扩大纳洛酮供应的可能性,本研究旨在评估澳大利亚药剂师:(1)对过量用药预防的支持程度;(2)纳洛酮供应的障碍和促进因素;(3)关于纳洛酮给药的知识。
对具有全国代表性的社区药房样本进行在线调查。
澳大利亚,2015年9月至11月。
共邀请1317名社区药剂师参与,收到595份回复(45.1%)。
我们评估了对减少伤害的态度、对过量用药预防的支持、对纳洛酮的态度和知识。我们测试了对减少伤害的态度与纳洛酮供应不同方面之间的关联。
药剂师愿意接受纳洛酮培训的有479人(80.5%),愿意凭处方提供纳洛酮的有537人(90.3%)。愿意非处方供应纳洛酮的较少(234人,40.8%)。对减少伤害的积极态度与更愿意凭处方供应纳洛酮[比值比(OR)=1.15,95%置信区间(CI)=1.11 - 1.19]和非处方供应(OR = 1.13,95%CI = 1.09 - 1.17)相关。很少有药剂师确信自己能识别合适的患者(203人,34.1%)并就过量用药和纳洛酮使用对他们进行教育(190人,31.9%)。纳洛酮知识平均得分在5分制中为1.8分(标准差1.7)。超过一半的样本认为时间不足、培训缺乏、知识不足和报销问题是提供纳洛酮的潜在障碍。
澳大利亚的社区药剂师似乎愿意供应纳洛酮。对纳洛酮药理学和给药知识水平较低凸显了培训药剂师进行过量用药预防的重要性。