Fu Dan, Zhang Zhen-Yong, Wang Lin, Zhou Xing-Tao, Yu Zhi-Qiang
a Department of Ophthalmology, Eye and ENT Hospital , Fudan University , Shanghai , PR China.
b Department of Ophthalmology , Shanghai University of Traditional Chinese Medicine , Shanghai , PR China.
Semin Ophthalmol. 2017;32(5):631-641. doi: 10.3109/08820538.2016.1142579. Epub 2016 Jul 1.
This retrospective study aimed to explore refractive regression and central corneal thickness (CCT) following laser-assisted subepithelial keratectomy (LASEK) performed for the correction of high myopia in eyes with thin corneas. Forty patients (19 male, 21 female; mean age, 28.5 years) representing 76 treated eyes were included. The mean optical zone was 6.10 ± 0.32 mm, and the mean ablation depth was 121.53 ± 15.48 µm. CCT was significantly greater three years after surgery than at three months after surgery (425.66 ± 15.44 vs. 385.20 ± 12.81, respectively; p<0.001). The mean change in CCT from three months to three years was 40.46 ± 14.02 µm. The SE at three years was greater than that at three months (p<0.001). Although there was refractive regression, these data suggest that LASEK may have utility in the correction of high myopia in eyes with thin corneas.
这项回顾性研究旨在探讨在薄角膜眼中进行准分子激光上皮瓣下角膜磨镶术(LASEK)矫正高度近视后的屈光回退和中央角膜厚度(CCT)。纳入了40例患者(19例男性,21例女性;平均年龄28.5岁),共76只接受治疗的眼睛。平均光学区为6.10±0.32毫米,平均消融深度为121.53±15.48微米。术后三年的CCT显著高于术后三个月(分别为425.66±15.44和385.20±12.81;p<0.001)。从术后三个月到三年,CCT的平均变化为40.46±14.02微米。术后三年的等效球镜度(SE)高于术后三个月(p<0.001)。尽管存在屈光回退,但这些数据表明LASEK在矫正薄角膜眼的高度近视方面可能具有实用性。