Mahajan R C, Sehgal R, Malla N, Ganguly N K
Indian J Med Res. 1989 Mar;89:100-4.
Dot-enzyme linked immunosorbent assay (Dot-ELISA) used for the serodiagnosis of both intestinal and extraintestinal amoebiasis, showed positivity in 94 per cent patients of amoebic liver abscess and 87.5 per cent of intestinal amoebiasis. Only one of the 18 normal controls was positive by Dot-ELISA test. This test showed good correlation with indirect haemagglutination test. As it is simple and easy to perform, the test appears to have great potential for the specific diagnosis of amoebiasis in peripheral hospitals and also at the field level where sophisticated immunodiagnostic facilities are not available.
用于肠道和肠外阿米巴病血清学诊断的斑点酶联免疫吸附测定（Dot-ELISA）显示，94%的阿米巴肝脓肿患者和87.5%的肠道阿米巴病患者呈阳性。18名正常对照者中只有1人通过Dot-ELISA检测呈阳性。该检测与间接血凝试验显示出良好的相关性。由于其操作简单易行，该检测在外围医院以及缺乏精密免疫诊断设施的现场层面对于阿米巴病的特异性诊断似乎具有巨大潜力。
