El Maataoui Aissam, Biaz Asmae, El Machtani Samira, Bouhsain Sanae, Dami Abdellah, El Maghraoui Abdellah, Ouzzif Zohra
Faculty of Medicine and Pharmacy, Ibn Zohr University, Agadir, Morocco.
Biochemistry Department, Faculty of Medicine and Pharmacy, Casablanca, Morocco.
Arch Osteoporos. 2016 Dec;11(1):24. doi: 10.1007/s11657-016-0279-y. Epub 2016 Jul 5.
This study aimed to compare the vitamin D status in healthy Moroccan men and women aged 50 years and older. A total of 186 Moroccan women and 68 men, who had no previous diagnosis of osteoporosis, were recruited prospectively. We found in this study a high prevalence of hypovitaminosis D with no difference between men and women.
The main purpose of this study was to describe and compare the vitamin D status, parathormone, calcium, and phosphate of healthy Moroccan men and women aged 50 years and older.
We conducted two cross-sectional studies, in postmenopausal women from October 2008 to November 2009 and in men over 50 years old, from December 2009 to August 2010. A total of 186 Moroccan women and 68 men, who had no previous diagnosis of osteoporosis, were recruited prospectively. For the definition of hypovitaminosis D, the preferred level for 25-hydroxyvitamin D (25(OH)D) insufficiency, which is now recommended by many experts, is 30 ng/mL (75 nmol/L), and the levels below 10 ng/ml (25 nmol/L) indicate deficiency.
The prevalence of vitamin D deficiency in men and women was 4.4 and 8.6 %, respectively, and the prevalence of vitamin D(25(OH) D) insufficiency in men and women were 85.2 and 77.4 %, respectively. In men and women, no correlations were found between intact parathormone (PTHi) and 25(OH) D (r = 0.056).
Despite a sunny environment, we found in this study a high prevalence of hypovitaminosis D (insufficiency + deficiency) in Moroccan men over 50 years old and postmenopausal women.
本研究旨在比较50岁及以上健康摩洛哥男性和女性的维生素D状况。前瞻性招募了总共186名摩洛哥女性和68名男性，他们之前均未被诊断出患有骨质疏松症。我们在本研究中发现维生素D缺乏症的患病率很高，男性和女性之间没有差异。
本研究的主要目的是描述和比较50岁及以上健康摩洛哥男性和女性的维生素D状况、甲状旁腺激素、钙和磷酸盐。
我们进行了两项横断面研究，一项是在2008年10月至2009年11月对绝经后女性进行的，另一项是在2009年12月至2010年8月对50岁以上男性进行的。前瞻性招募了总共186名摩洛哥女性和68名男性，他们之前均未被诊断出患有骨质疏松症。对于维生素D缺乏症的定义，许多专家目前推荐的25-羟基维生素D（25(OH)D）不足的首选水平为30 ng/mL（75 nmol/L），低于10 ng/ml（25 nmol/L）的水平表示缺乏。
男性和女性维生素D缺乏的患病率分别为4.4%和8.6%，男性和女性维生素D（25(OH)D）不足的患病率分别为85.2%和77.4%。在男性和女性中，未发现完整甲状旁腺激素（PTHi）与25(OH)D之间存在相关性（r = 0.056）。
尽管环境阳光充足，但我们在本研究中发现，50岁以上的摩洛哥男性和绝经后女性中维生素D缺乏症（不足 + 缺乏）的患病率很高。
