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巴西人的维生素D状况及其与甲状旁腺激素浓度的关联。

Vitamin D Status and Its Association with Parathyroid Hormone Concentration in Brazilians.

作者信息

Martins Juliana Sálvio, Palhares Magda de Oliveira, Teixeira Octávio Cury Mayrink, Gontijo Ramos Mariana

机构信息

College of Human, Social and Health Sciences, Universidade Fumec, Belo Horizonte, MG, Brazil.

出版信息

J Nutr Metab. 2017;2017:9056470. doi: 10.1155/2017/9056470. Epub 2017 Feb 7.

Abstract

Vitamins are organic compounds that play a vital role in the control of metabolic processes. The D complex is considered a nutrient with a hormonal action and has an important participation in the constant maintenance of serum and extracellular calcium levels. The present study aims to analyze the results of 105.588 vitamin D (25(OH)D) measurements obtained from a database from a clinical analysis laboratory in Brazil, between the years of 2011 and 2013. The values of 25(OH)D were correlated with age, gender, and values of PTH. The results show a high prevalence of values of 25(OH)D considered inadequate, characterizing 76% of the studied population. It was observed that 26,5% of the individuals had deficiency and 49,5% had insufficiency of vitamin D. It was also shown that there was a negative correlation between 25(OH)D and PTH levels. In conclusion, this study is in accordance with others that show a high prevalence of vitamin D deficiency in different populations and alerts us for the importance of these measurements and analysis in clinical practice and as a base for diagnosis and treatment of hypovitaminosis.

摘要

维生素是在代谢过程控制中起关键作用的有机化合物。维生素D复合物被认为是一种具有激素作用的营养素,并且在血清和细胞外钙水平的持续维持中具有重要作用。本研究旨在分析2011年至2013年间从巴西一家临床分析实验室的数据库中获得的105588次维生素D(25(OH)D)测量结果。25(OH)D的值与年龄、性别和甲状旁腺激素(PTH)的值相关。结果显示,25(OH)D值被认为不足的情况很普遍,占研究人群的76%。观察到26.5%的个体存在维生素D缺乏,49.5%的个体存在维生素D不足。还表明25(OH)D与PTH水平之间存在负相关。总之,本研究与其他研究一致,表明不同人群中维生素D缺乏的患病率很高,并提醒我们这些测量和分析在临床实践中的重要性,以及作为维生素缺乏症诊断和治疗依据的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c315/5318626/616808ce04c7/JNME2017-9056470.001.jpg

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