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墨西哥北部青少年的血脂谱、血脂异常患病率及相关危险因素

Serum Lipid Profile, Prevalence of Dyslipidaemia, and Associated Risk Factors Among Northern Mexican Adolescents.

作者信息

Bibiloni Maria Del Mar, Salas Rogelio, De la Garza Yolanda E, Villarreal Jesus Z, Sureda Antoni, Tur Josep A

机构信息

*Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands, and CIBEROBN (Physiopathology of Obesity and Nutrition), Palma de Mallorca, Spain †Faculty of Public Health Nutrition, Autonomous University of Nuevo León, Monterrey ‡Department of Health of the State of Nuevo, León, Mexico.

出版信息

J Pediatr Gastroenterol Nutr. 2016 Nov;63(5):544-549. doi: 10.1097/MPG.0000000000001325.

Abstract

BACKGROUND

The increase in overweight and obese children and adolescents may be linked to increased rates of dyslipidaemia. The aim was to assess the serum lipid profile, the prevalence of dyslipidaemia, and associated risk factors among the North Mexican adolescent population.

METHODS

Two hundred and ninety-three subjects (47.8% girls) ages 11 to 16 years took part in the Nuevo León State Survey of Nutrition and Health 2011-2012. According to the 2011 Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents, dyslipidaemia was defined as a presence of ≥1 of the following levels (mg/dL): Total cholesterol ≥200, low-density lipoprotein cholesterol ≥130, non-high-density lipoprotein cholesterol <40, and triglyceride ≥130.

RESULTS

The overall frequency of dyslipidaemia was 48.8% with no differences between sexes. Adolescents with high body mass index were more likely to have at least 1 abnormal lipid level (overweight: odds ratio [OR]: 2.07; 95% confidence interval [CI]: 1.14-3.77, P < 0.05; obesity: OR: 2.21, 95% CI: 1.11-4.41, P < 0.05) than those with normal weight. Abdominally subjects with obesity were also more likely to have at least 1 abnormal lipid level (OR: 2.30; 95% CI: 1.35-3.91, P < 0.01) than their leaner counterparts.

CONCLUSIONS

Half of Mexican adolescents living in the State of Nuevo León have at least 1 abnormal lipid concentration. Low HDL-chol level was the most common dyslipidaemia. Body mass index and abdominal obesity were associated with the prevalence of at least 1 abnormal lipid level.

摘要

背景

超重和肥胖儿童及青少年数量的增加可能与血脂异常率上升有关。目的是评估墨西哥北部青少年人群的血清脂质谱、血脂异常患病率及相关危险因素。

方法

293名年龄在11至16岁的受试者(47.8%为女孩)参与了2011 - 2012年新莱昂州营养与健康调查。根据2011年儿童和青少年心血管健康与风险降低综合指南专家小组的标准,血脂异常定义为存在以下至少一项水平(mg/dL):总胆固醇≥200、低密度脂蛋白胆固醇≥130、非高密度脂蛋白胆固醇<40以及甘油三酯≥130。

结果

血脂异常的总体发生率为48.8%,男女之间无差异。体重指数高的青少年比体重正常的青少年更有可能至少有一项血脂水平异常(超重:比值比[OR]:2.07;95%置信区间[CI]:1.14 - 3.77,P<0.05;肥胖:OR:2.21,95%CI:1.11 - 4.41, P<0.05)。腹部肥胖的受试者也比体型较瘦的受试者更有可能至少有一项血脂水平异常(OR:2.30;95%CI:1.35 - 3.91,P<0.01)。

结论

居住在新莱昂州的墨西哥青少年中有一半至少有一项血脂浓度异常。低高密度脂蛋白胆固醇水平是最常见的血脂异常类型。体重指数和腹部肥胖与至少一项血脂水平异常的患病率相关。

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