Staudinger T
Universitätsklinik für Innere Medizin I, Intensivstation 13.i2, Allgemeines Krankenhaus der Stadt Wien/Medizinische Universität Wien, Währinger Gürtel 18-20, 1090, Wien, Österreich.
Med Klin Intensivmed Notfmed. 2018 Jun;113(5):401-408. doi: 10.1007/s00063-016-0182-8. Epub 2016 Jul 5.
Technical developments as well as the experiences during the 2009 influenza pandemia have led to an increased and safer use of extracorporeal gas exchange. Indications are expanding as new systems with the main goal of CO elimination have entered the market, thus, broadening the range of systems in addition to classic "high flow" extracorporeal membrane oxygenation (ECMO), although evidence for many suggested indications is sparse or lacking. However, recent research has shed light into the pathophysiology and interaction between the organism and the extracorporeal systems. Upcoming indications like avoiding intubation and mechanical ventilation or reducing invasiveness of ventilation are being evaluated. Novel data and technical advances will keep perspectives of extracorporeal gas exchange dynamic and exciting.
技术发展以及2009年流感大流行期间的经验，使得体外气体交换的使用更加广泛且安全。随着以消除二氧化碳为主要目标的新系统进入市场，适应症正在不断扩大，从而拓宽了除经典的“高流量”体外膜肺氧合（ECMO）之外的系统范围，尽管许多建议适应症的证据稀少或缺乏。然而，最近的研究已经阐明了机体与体外系统之间的病理生理学及相互作用。诸如避免插管和机械通气或降低通气侵入性等新出现的适应症正在接受评估。新的数据和技术进步将使体外气体交换的前景保持动态且令人兴奋。
