Lai Yo-Liang, Wu Chun-Yi, Chao K S Clifford
Department of Radiation Oncology, China Medical University Hospital, China Medical University, Taichung, Taiwan.
Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan.
Int J Clin Oncol. 2016 Aug;21(4):626-632. doi: 10.1007/s10147-016-1000-2. Epub 2016 Jul 6.
Radiation therapy is one of the most effective tools for cancer treatment. In recent years, intensity-modulated radiation therapy has become increasingly popular in that target dose-escalation can be done while sparing adjacent normal tissues. For this reason, the development of measures to pave the way for accurate target delineation is of great interest. With the integration of functional information obtained by biological imaging with radiotherapy, strategies using advanced biological imaging to visualize metabolic pathways and to improve therapeutic index and predict treatment response are discussed in this article.
放射治疗是癌症治疗最有效的工具之一。近年来，调强放射治疗越来越受欢迎，因为在保护相邻正常组织的同时可以提高靶区剂量。因此，开发为精确靶区勾画铺平道路的措施备受关注。本文讨论了将生物成像获得的功能信息与放射治疗相结合，利用先进生物成像可视化代谢途径、提高治疗指数和预测治疗反应的策略。
