Bahn S L, Goveia G, Bitterman P, Bahn A N
Oral Surg Oral Med Oral Pathol. 1978 Apr;45(4):549-59. doi: 10.1016/0030-4220(78)90036-1.
Circumstantial evidence has strongly implicated dental manipulation as an etiologic factor in the development of infective endocarditis. The introduction of human oral streptococci via the oral cavity in rabbits with vegetative cardiac lesions yields a 94 per cent incidence of infective endocarditis, if the number of inoculated organisms is above a threshold level of 10(7).
间接证据有力地表明,牙科操作是感染性心内膜炎发生的一个病因。在患有赘生性心脏病变的兔子中,经口腔引入人类口腔链球菌,如果接种的微生物数量高于10⁷的阈值水平,感染性心内膜炎的发生率为94%。