de Wit Hugo A J M, Hurkens Kim P G M, Mestres Gonzalvo Carlota, Smid Machiel, Sipers Walther, Winkens Bjorn, Mulder Wubbo J, Janknegt Rob, Verhey Frans R, van der Kuy Paul-Hugo M, Schols Jos M G A
Department of Clinical Pharmacy and Toxicology, Zuyderland Medical Centre, Henri Dunantstraat 5, 6419 PC Heerlen, The Netherlands.
Department of Internal Medicine, Section of Geriatric Medicine, Zuyderland Medical Centre, Sittard-Geleen, The Netherlands.
Springerplus. 2016 Jun 24;5(1):871. doi: 10.1186/s40064-016-2376-1. eCollection 2016.
First, to estimate the added value of a clinical decision support system (CDSS) in the performance of medication reviews in hospitalised elderly. Second, to identify the limitations of the current CDSS by analysing generated drug-related problems (DRPs).
Medication reviews were performed in patients admitted to the geriatric ward of the Zuyderland medical centre. Additionally, electronically available patient information was introduced into a CDSS. The DRP notifications generated by the CDSS were compared with those found in the medication review. The DRP notifications were analysed to learn how to improve the CDSS.
A total of 223 DRP strategies were identified during the medication reviews. The CDSS generated 70 clinically relevant DRP notifications. Of these DRP notifications, 63 % (44) were also found during the medication reviews. The CDSS generated 10 % (26) new DRP notifications and conveyed 28 % (70) of all 249 clinically relevant DRPs that were found. Classification of the CDSS generated DRP notifications related to 'medication error type' revealed that 'contraindications/interactions/side effects' and 'indication without medication' were the main categories not identified during the manual medication review. The error types 'medication without indication', 'double medication', and 'wrong medication' were mostly not identified by the CDSS.
The CDSS used in this study is not yet sufficiently advanced to replace the manual medication review, though it does add value to the manual medication review. The strengths and weaknesses of the current CDSS can be determined according to the medication error types.
第一,评估临床决策支持系统(CDSS)在老年住院患者用药评估中的附加价值。第二,通过分析产生的药物相关问题(DRP)来确定当前CDSS的局限性。
对祖德兰德医疗中心老年病房收治的患者进行用药评估。此外,将电子可得的患者信息输入到一个CDSS中。将CDSS生成的DRP通知与用药评估中发现的通知进行比较。对DRP通知进行分析,以了解如何改进CDSS。
在用药评估期间共确定了223条DRP策略。CDSS生成了70条具有临床相关性的DRP通知。在这些DRP通知中,63%(44条)也在用药评估中被发现。CDSS生成了10%(26条)新的DRP通知,并传达了所发现的所有249条具有临床相关性的DRP中的28%(70条)。对CDSS生成的与“用药错误类型”相关的DRP通知进行分类后发现,“禁忌症/相互作用/副作用”和“有适应症但未用药”是在人工用药评估中未识别出的主要类别。“无适应症用药”“重复用药”和“用药错误”等错误类型大多未被CDSS识别。
本研究中使用的CDSS尚未足够先进到可以取代人工用药评估,不过它确实为人工用药评估增加了价值。可以根据用药错误类型来确定当前CDSS的优势和劣势。