Allman R, Sousa J, Walker M W, Laughon M M, Spitzer A R, Clark R H
Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA.
Department of Biomedical Sciences, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA.
J Perinatol. 2016 Oct;36(10):901-5. doi: 10.1038/jp.2016.99. Epub 2016 Jul 7.
The purpose of this study is to evaluate recent trends in prevalence of gastroschisis among infants admitted for neonatal intensive care in the United States.
Retrospective review of a de-identified patient data. The current study extends our observations through the end of 2007 to 2015.
During the study period (1 January 1997 to 12 December 2015), there were 1 158 755 total discharges; 6023 (5.2/1000) had gastroschisis and 1885 (1.6/1000) had an omphalocele. Between 1997 and 2008, the reported rate of gastroschisis increased from 2.9 to 6.4/1000 discharges. From 2008 to 2011, the values have slowly decreased from 6.4 to 4.7/1000 discharges and since 2011 have been stable. The largest drop in the prevalence was in mothers who were <20 years old. In contrast, the reported rate of omphalocele was stable at 1 to 2/1000 discharges.
The prevalence of gastroschisis increased from 1997 to 2008, and then declined thereafter.
本研究旨在评估在美国因新生儿重症监护而入院的婴儿中腹裂患病率的近期趋势。
对去识别化的患者数据进行回顾性分析。本研究将我们的观察时间从2007年底延长至2015年。
在研究期间（1997年1月1日至2015年12月12日），共有1158755例出院病例；其中6023例（5.2/1000）患有腹裂，1885例（1.6/1000）患有脐膨出。1997年至2008年期间，腹裂报告发病率从2.9/1000出院病例增加至6.4/1000出院病例。2008年至2011年，该数值从6.4/1000出院病例缓慢降至4.7/1000出院病例，自2011年以来一直稳定。患病率下降幅度最大的是年龄小于20岁的母亲。相比之下，脐膨出的报告发病率稳定在1至2/1000出院病例。
腹裂患病率在1997年至2008年期间上升，此后下降。
