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气压、湿度与中风发生：一项系统评价与荟萃分析

Air Pressure, Humidity and Stroke Occurrence: A Systematic Review and Meta-Analysis.

作者信息

Cao Yongjun, Wang Xia, Zheng Danni, Robinson Thompson, Hong Daqing, Richtering Sarah, Leong Tzen Hugh, Salam Abdul, Anderson Craig, Hackett Maree L

机构信息

Department of Neurology, The Second Affiliated Hospital of Soochow University, No.1055, Sanxiang Rd., Suzhou 215004, China.

The George Institute for Global Health, P.O. Box M201, Missenden Road, Sydney, NSW 2050, Australia.

出版信息

Int J Environ Res Public Health. 2016 Jul 5;13(7):675. doi: 10.3390/ijerph13070675.

DOI:10.3390/ijerph13070675
PMID:27399733
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4962216/
Abstract

BACKGROUND/AIMS: An influence of climate upon stroke risk is biologically plausible and supported by epidemiological evidence. We aimed to determine whether air pressure (AP) and humidity are associated with hospital stroke admission.

METHODS

We searched MEDLINE, Embase, PsycINFO, CINAHL, Web of Science, and GEOBASE, from inception to 16 October 2015 to identify relevant population-based observational studies. Where possible, data were pooled for meta-analysis with odds ratios (OR) and corresponding 95% confidence intervals (CI) by means of the random-effect method.

RESULTS

We included 11 studies with a total of 314,385 patients. The effect of AP was varied across studies for ischemic stroke (IS) and subarachnoid haemorrhage (SAH). Pooled ORs (95%CI) associated with 1 hPa increase in AP for the risk of IS, intracerebral hemorrhage (ICH) and SAH were 1.00 (0.99-1.01), 1.01 (0.99-1.02) and 1.02 (0.97-1.07) respectively. The pooled ORs (95%CI) associated with 1 percent increase in humidity for the risk of IS and ICH were 1.00 (1.00-1.01) and 1.00 (0.99-1.01) respectively.

CONCLUSION

This review shows that there is no evidence of a relationship between AP or humidity and the occurrence of hospital admission for stroke. Further research is needed to clarify the extent and nature of any relationship between AP, humidity and stroke in different geographical areas.

摘要

背景/目的：气候对中风风险的影响在生物学上是合理的，且有流行病学证据支持。我们旨在确定气压（AP）和湿度是否与医院中风入院率相关。

方法

我们检索了MEDLINE、Embase、PsycINFO、CINAHL、Web of Science和GEOBASE数据库，检索时间从建库至2015年10月16日，以识别相关的基于人群的观察性研究。在可能的情况下，通过随机效应方法对数据进行汇总，以计算比值比（OR）和相应的95%置信区间（CI）进行荟萃分析。

结果

我们纳入了11项研究，共314385例患者。气压对缺血性中风（IS）和蛛网膜下腔出血（SAH）的影响在不同研究中有所不同。与气压每升高1 hPa相关的IS、脑出血（ICH）和SAH风险的汇总OR（95%CI）分别为1.00（0.99 - 1.01）、1.01（0.99 - 1.02）和1.02（0.97 - 1.07）。与湿度每升高1%相关的IS和ICH风险的汇总OR（95%CI）分别为1.00（1.00 - 1.01）和1.00（0.99 - 1.01）。

结论

本综述表明，没有证据表明气压或湿度与中风住院发生率之间存在关联。需要进一步研究以阐明不同地理区域中气压、湿度与中风之间任何关联的程度和性质。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a5f/4962216/d34d5e0102ca/ijerph-13-00675-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a5f/4962216/db6cca30c2c5/ijerph-13-00675-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a5f/4962216/78ef36b9d4e7/ijerph-13-00675-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a5f/4962216/d34d5e0102ca/ijerph-13-00675-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a5f/4962216/db6cca30c2c5/ijerph-13-00675-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a5f/4962216/78ef36b9d4e7/ijerph-13-00675-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a5f/4962216/d34d5e0102ca/ijerph-13-00675-g003.jpg

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