Erb Tobias J, Zarzycki Jan
Max Planck Institute for Terrestrial Microbiology, Biochemistry & Synthetic Biology of Microbial Metabolism Group, Karl-von-Frisch-Str. 10, 35043 Marburg, Germany; LOEWE Center for Synthetic Microbiology (SYNMIKRO), Philipps University Marburg, 35043 Marburg, Germany.
Max Planck Institute for Terrestrial Microbiology, Biochemistry & Synthetic Biology of Microbial Metabolism Group, Karl-von-Frisch-Str. 10, 35043 Marburg, Germany.
Curr Opin Chem Biol. 2016 Oct;34:72-79. doi: 10.1016/j.cbpa.2016.06.026. Epub 2016 Jul 9.
There is an urgent need to improve agricultural productivity to secure future food and biofuel supply. Here, we summarize current approaches that aim at improving photosynthetic CO-fixation. We critically review, compare and comment on the four major lines of research towards this aim, which focus on (i) improving RubisCO, the CO-fixing enzyme in photosynthesis, (ii) implementing CO-concentrating mechanisms, (iii) establishing synthetic photorespiration bypasses, and (iv) engineering synthetic CO-fixation pathways.
迫切需要提高农业生产力以确保未来的粮食和生物燃料供应。在此，我们总结了旨在提高光合碳固定的当前方法。我们对实现这一目标的四大研究方向进行了批判性回顾、比较和评论，这些方向聚焦于：（i）改进光合作用中固定二氧化碳的酶——核酮糖-1,5-二磷酸羧化酶/加氧酶（RubisCO）；（ii）实施二氧化碳浓缩机制；（iii）建立合成光呼吸旁路；以及（iv）设计合成碳固定途径。
