印度尼西亚亚齐省社区参与登革热研究的意愿
Community Willingness to Participate in a Dengue Study in Aceh Province, Indonesia.
作者信息
Harapan Harapan, Anwar Samsul, Bustaman Aslam, Radiansyah Arsil, Angraini Pradiba, Fasli Riny, Salwiyadi Salwiyadi, Bastian Reza Akbar, Oktiviyari Ade, Akmal Imaduddin, Iqbalamin Muhammad, Adil Jamalul, Henrizal Fenni, Darmayanti Darmayanti, Pratama Rovy, Fajar Jonny Karunia, Setiawan Abdul Malik, Imrie Allison, Kuch Ulrich, Groneberg David Alexander, Sasmono R Tedjo, Dhimal Meghnath, Müller Ruth
机构信息
Medical Research Unit, School of Medicine, Syiah Kuala University, Banda Aceh, Indonesia.
Tropical Disease Centre, School of Medicine, Syiah Kuala University, Banda Aceh, Indonesia.
出版信息
PLoS One. 2016 Jul 12;11(7):e0159139. doi: 10.1371/journal.pone.0159139. eCollection 2016.
BACKGROUND
Dengue virus infection is the most rapidly spreading vector-borne disease in the world. Essential research on dengue virus transmission and its prevention requires community participation. Therefore, it is crucial to understand the factors that are associated with the willingness of communities in high prevalence areas to participate in dengue research. The aim of this study was to explore factors associated with the willingness of healthy community members in Aceh province, Indonesia, to participate in dengue research that would require phlebotomy.
METHODOLOGY/PRINCIPAL FINDINGS: A community-based cross-sectional study was carried out in nine regencies and municipalities of Aceh from November 2014 to March 2015. Interviews using a set of validated questionnaires were conducted to collect data on demography, history of dengue infection, socioeconomic status, and knowledge, attitude and practice regarding dengue fever. Two-step logistic regression and Spearman's rank correlation (rs) analysis were used to assess the influence of independent variables on dependent variables. Among 535 participants, less than 20% had a good willingness to participate in the dengue study. The factors associated with good willingness to participate were being female, working as a civil servant, private employee or entrepreneur, having a high socioeconomic status and good knowledge, attitude and practice regarding dengue. Good knowledge and attitude regarding dengue were positive independent predictors of willingness to participate (OR: 2.30 [95% CI: 1.36-3.90] and 3.73 [95% CI: 2.24-6.21], respectively).
CONCLUSION/SIGNIFICANCE: The willingness to participate in dengue research is very low among community members in Aceh, and the two most important associated factors are knowledge and attitude regarding dengue. To increase participation rate, efforts to improve the knowledge and attitude of community members regarding dengue fever and dengue-related research is required before such studies are launched.
背景
登革热病毒感染是世界上传播速度最快的媒介传播疾病。登革热病毒传播及其预防的基础研究需要社区参与。因此，了解高流行地区社区参与登革热研究意愿的相关因素至关重要。本研究的目的是探讨印度尼西亚亚齐省健康社区成员参与需要进行静脉穿刺的登革热研究意愿的相关因素。
方法/主要发现：2014年11月至2015年3月在亚齐的9个县和市开展了一项基于社区的横断面研究。使用一套经过验证的问卷进行访谈，以收集有关人口统计学、登革热感染史、社会经济地位以及关于登革热的知识、态度和行为的数据。采用二步逻辑回归和Spearman等级相关（rs）分析来评估自变量对因变量的影响。在535名参与者中，不到20%的人有良好的参与登革热研究的意愿。与良好参与意愿相关的因素包括女性、公务员、私企员工或企业家身份、高社会经济地位以及对登革热有良好的知识、态度和行为。对登革热的良好知识和态度是参与意愿的积极独立预测因素（OR分别为：2.30 [95% CI：1.36 - 3.90]和3.73 [95% CI：2.24 - 6.21]）。
结论/意义：亚齐社区成员参与登革热研究的意愿非常低，两个最重要的相关因素是对登革热的知识和态度。为提高参与率，在开展此类研究之前，需要努力改善社区成员对登革热及登革热相关研究的知识和态度。
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