印度东北部伯氏疏螺旋体的血清阳性率
Seroprevalence of Borrelia burgdorferi in North Eastern India.
作者信息
Praharaj A K, Jetley S, Kalghatgi A T
机构信息
PDMS(HS), DGMS Navy, Naval HQ, Delhi.
Ex-Classified Specialist (Pathology), AFTC, Delhi Cantt.
出版信息
Med J Armed Forces India. 2008 Jan;64(1):26-8. doi: 10.1016/S0377-1237(08)80140-2. Epub 2011 Jul 21.
BACKGROUND
There is paucity of data on Lyme disease in India. A seroprevalence study of B burgdorferi infection was carried out in North-Eastern states of India to assess the same.
METHODS
Sera from 500 individuals of North-Eastern states of India were tested for IgG antibody by enzyme linked immunosorbent assay using commercial kits containing recombinant antigen.
RESULT
Out of 500 persons, 65 (13%) were positive for B burgdorferi specific lgG Females showed higher positivity rate as compared to males (15.86% vs 10.95%). Higher prevalence rate was observed in the age group of 15-30 years in both sexes (11.48% in male and 18.69% in female). Arunachal Pradesh showed higher seroprevalence rate (17.8%) as compared to other North-Eastern states (8.46-9.6%).
CONCLUSION
Seropositivity to B burgdorferi suggests infection by the organism and presence of Lyme disease in these areas. Further population and vector biology studies are required to find out the exact species involved in transmission of the organism.
背景
关于印度莱姆病的数据匮乏。在印度东北部各邦开展了一项针对伯氏疏螺旋体感染的血清阳性率研究以评估该病情况。
方法
使用含有重组抗原的商用试剂盒，通过酶联免疫吸附测定法对来自印度东北部各邦的500名个体的血清进行IgG抗体检测。
结果
在500人中，65人（13%）伯氏疏螺旋体特异性IgG呈阳性。女性的阳性率高于男性（15.86%对10.95%）。在15至30岁年龄组中，两性的患病率均较高（男性为11.48%，女性为18.69%）。与其他东北部邦（8.46 - 9.6%）相比，阿鲁纳恰尔邦的血清阳性率更高（17.8%）。
结论
伯氏疏螺旋体血清阳性表明这些地区存在该病原体感染及莱姆病。需要进一步开展人群和病媒生物学研究以查明参与该病原体传播的确切物种。
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