van Biljon G
Department of Paediatrics, University of Pretoria.
S Afr Med J. 1989 Jul 1;76(1):34-5.
The clinical presentation and management of a young boy with acute non-oliguric renal failure associated with a nonsteroidal anti-inflammatory drug (NSAID), ibuprofen, prescribed for the relief of pain is described. Deterioration of renal function developed unexpectedly but fortunately withdrawal of the drug and appropriate management resulted in spontaneous recovery. All NSAIDs have the ability to interfere with renal function and their administration should probably be avoided in children with pre-existing dehydration or with conditions that predispose to an increased risk of renal insufficiency.
本文描述了一名年轻男孩的临床表现及治疗情况，该男孩因服用非甾体抗炎药布洛芬缓解疼痛而出现急性非少尿性肾衰竭。肾功能意外恶化，但幸运的是停药并给予适当治疗后实现了自发恢复。所有非甾体抗炎药都有干扰肾功能的能力，对于已有脱水情况或有肾功能不全风险增加因素的儿童，可能应避免使用这类药物。
