Lecic Jelena, Cakic Sasa, Janjic Pavlovic Ognjenka, Cicmil Ana, Vukotic Olivera, Petrovic Vanja, Cicmil Smiljka
a Department of Periodontology and Oral Medicine , University of East Sarajevo, Faculty of Medicine, Dentistry Program , Foca , Bosnia and Herzegovina ;
b Department of Periodontology and Oral Medicine , University of Belgrade, Faculty of Dental Medicine , Belgrade , Serbia ;
Acta Odontol Scand. 2016 Aug;74(6):502-7. doi: 10.1080/00016357.2016.1206964. Epub 2016 Jul 13.
The aim of this study was to evaluate clinical efficacy of different chlorhexidine gluconate (CHX) preparations applied subgingivally as an adjunct to scaling and root planing (SRP).
A total of 120 periodontal pockets was included in this randomized, controlled, split mouth designed study. According to protocols used in treatment, periodontal pockets were assigned to experimental and control groups as follows: CHX solution as an addition to SRP versus control SRP group; CHX gel as an addition to SRP versus control SRP; CHX chip as an addition to SRP versus control SRP group. Following clinical parameters were recorded at baseline, one and three months after the baseline: plaque index (PI), probing pocket depth (PPD), bleeding index (BI) and clinical attachment level (CAL).
The most significant improvements were found concerning PI in CHX solution with SRP and CHX gel with SRP groups over controls at one month recall, as well as concerning BI and PPD in CHX chip with SRP group over SRP alone at three-month recall.
Results of this study favour combination therapy using CHX chip as an adjunct to SRP due to greater improvements in BI and PPD compared to those obtained by SRP alone in the treatment of chronic periodontitis.
本研究旨在评估不同葡萄糖酸氯己定(CHX)制剂龈下应用作为龈上洁治和根面平整(SRP)辅助治疗的临床疗效。
本随机、对照、双侧设计研究共纳入120个牙周袋。根据治疗方案,牙周袋被分为试验组和对照组如下:CHX溶液联合SRP组与单纯SRP对照组;CHX凝胶联合SRP组与单纯SRP对照组;CHX芯片联合SRP组与单纯SRP对照组。在基线、基线后1个月和3个月记录以下临床参数:菌斑指数(PI)、探诊深度(PPD)、出血指数(BI)和临床附着水平(CAL)。
在1个月复诊时,CHX溶液联合SRP组和CHX凝胶联合SRP组的PI相比对照组有最显著改善;在3个月复诊时,CHX芯片联合SRP组的BI和PPD相比单纯SRP组有更显著改善。
本研究结果支持在慢性牙周炎治疗中使用CHX芯片联合SRP的联合治疗方法,因为与单纯SRP相比,其在BI和PPD方面有更大改善。