Lazreg Sihem, Delcourt Cécile, Zeggane Sihem, Sanchez Alice, Ziani Assia, Daghbouche Mounir, Benmoussa Salaheddine, Mokrani Karim, Billah Mekki Moatez, Renault Didier, Battaglia Parodi Maurizio, Bandello Francesco, Nouri Mohamed Tahar
Ophthalmology, Private Practice, Blida, Algeria.
Ophthalmic Res. 2016;56(3):145-54. doi: 10.1159/000446844. Epub 2016 Jul 14.
To determine the risk factors for age-related macular degeneration (AMD) in Algerians, and compare these data with those on North Africans living in Italy.
All patients over 55 years of age consulting one of the 23 involved Algerian ophthalmologists were invited to participate, and 1,183 patients were included. Data collection was standardized based on the Simplified Théa Risk Assessment Scale (STARS) questionnaire. A similar study was conducted in North Africans living in Italy (n = 1,011). Patients with only soft drusen and/or pigmentary abnormalities were classified as early AMD, and patients with geographic atrophy and/or neovascular AMD were classified as late AMD.
In the final multivariate model, risk for early and/or late AMD was significantly increased with older age, family history of AMD, Black ethnicity, atherosclerosis, beer consumption, high fruit consumption, cataract surgery, myopia, and hyperopia. High consumption of green vegetables was associated with lower risk for both early and late AMD. In comparison with North Africans from Italy, Algerians generally had a healthier profile (younger, less obesity, smoking, and cardiovascular diseases, and higher consumption of fruits and vegetables) and a lower risk for AMD.
This study documents risk factors for AMD in North-African populations for the first time.
确定阿尔及利亚人年龄相关性黄斑变性（AMD）的危险因素，并将这些数据与居住在意大利的北非人的数据进行比较。
邀请所有55岁以上咨询23位参与研究的阿尔及利亚眼科医生之一的患者参与，共纳入1183例患者。基于简化的西娅风险评估量表（STARS）问卷进行标准化数据收集。在居住在意大利的北非人（n = 1011）中进行了类似研究。仅有软性玻璃膜疣和/或色素异常的患者被分类为早期AMD，有地图样萎缩和/或新生血管性AMD的患者被分类为晚期AMD。
在最终的多变量模型中，早期和/或晚期AMD的风险随着年龄增长、AMD家族史、黑人种族、动脉粥样硬化、饮用啤酒、高水果摄入量、白内障手术、近视和远视而显著增加。高摄入量的绿色蔬菜与早期和晚期AMD的较低风险相关。与来自意大利的北非人相比，阿尔及利亚人总体上健康状况更好（更年轻、肥胖、吸烟和心血管疾病更少，水果和蔬菜摄入量更高）且AMD风险更低。
本研究首次记录了北非人群中AMD的危险因素。
