Sinopal'nikov A I, Alekseev V G
Ter Arkh. 1989;61(3):114-8.
The data are presented on the incidence and the course of coronary heart disease (CHD) in senior group patients with concomitant bronchial asthma (BA). The clinical symptomatology in the given case differs in some respects from the classical concepts of the conventional course of the disease under consideration. The patients with concomitant BA show, in a considerable number of cases, (21.9 percent), an asymptomatic course of CHD. Among the patients with the angina pectoris syndrome, the proportion of the patients with functional class I angina pectoris is relatively low. Among such patients, there predominate subjects with a brief history of CHD (lasting less than 5 years). The incidence of the arrhythmic patterns of CHD (paroxysmal or constant atrial fibrillation, stable ventricular premature heart beat of high brades) is not great either. The clinical interrelations between CHD and BA when combined are characterized, as a rule, by the fact that exacerbation of one of the diseases is accompanied by regression of the symptoms of the concomitant pathology that withdraws as if to the background. The data obtained appear to suggest that the given group of the patients require a goal-oriented instrumental examination (exercise tests, ECG-monitoring, etc.) followed by administration of adequate coordinated drug treatment.
本文呈现了老年合并支气管哮喘(BA)患者冠心病(CHD)的发病率及病程情况。该病例中的临床症状在某些方面与所考虑疾病的传统病程经典概念有所不同。相当一部分(21.9%)合并BA的患者表现为冠心病无症状病程。在心绞痛综合征患者中,I级心绞痛患者的比例相对较低。此类患者中,冠心病病史较短(持续时间少于5年)的患者占多数。冠心病心律失常类型(阵发性或持续性心房颤动、高度稳定的室性早搏)的发生率也不高。通常情况下,CHD与BA合并时的临床相互关系表现为,其中一种疾病的加重伴随着伴随病变症状的消退,仿佛退居幕后。所获得的数据似乎表明,该组患者需要进行有针对性的仪器检查(运动试验、心电图监测等),随后给予适当的协同药物治疗。