Chiriat'ev E A, Leonova O P, Byshevskiĭ A Sh
Ukr Biokhim Zh (1978). 1989 Jan-Feb;61(1):3-9.
The study is devoted to the interaction of peptide inhibitor of fibrin self-assemblage with two forms of fibrin monomer: deprived of fibrinopeptides A and preserving fibrinopeptides B (desAA-monomer) and fully activated (desAABB-monomer). It is shown that peptide inhibitor hinders the coagulative conversion of fibrinogen by thrombin, limiting the enzymic and nonenzymic stages of the process. The indispensible condition for the formation of inhibitor-monomeric fibrin associates is a preliminary modification of fibrinogen by thrombin.
不含纤维蛋白肽A但保留纤维蛋白肽B的（desAA-单体）和完全活化的（desAABB-单体）。结果表明，肽抑制剂阻碍凝血酶介导的纤维蛋白原的凝血转化，限制该过程的酶促和非酶促阶段。抑制剂-纤维蛋白单体复合物形成的必要条件是凝血酶对纤维蛋白原的预先修饰。
