血液凝固过程中纤维蛋白原向纤维蛋白的两步转变。
A two-step fibrinogen--fibrin transition in blood coagulation.
作者信息
Blombäck B, Hessel B, Hogg D, Therkildsen L
出版信息
Nature. 1978 Oct 12;275(5680):501-5. doi: 10.1038/275501a0.
DOI:10.1038/275501a0
PMID:692730
Abstract
The kinetics of the thrombin-catalysed release of fibrino-peptides A and B from human fibrinogen have been investigated and a mechanism correlating the release of fibrinopeptides to fibrin formation is presented. The sequential release of fibrinopeptides results in sequential activation of two sets of polymerisation sites.
摘要
已对凝血酶催化人纤维蛋白原释放纤维蛋白肽A和B的动力学进行了研究，并提出了一种将纤维蛋白肽释放与纤维蛋白形成相关联的机制。纤维蛋白肽的顺序释放导致两组聚合位点的顺序激活。
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