Vigo Alessandro, Balagna Roberto, Brazzi Luca, Costagliola Giulia, Gregoretti Cesare, Lupica Maria Maddalena, Noce Silvia
Department of Anaesthesia and Intensive Care, Città della Salute e della Scienza.
Department of Anesthesia and Intensive Care, DiBiMed, Policlinico P. Giaccone, University of Palermo, Palermo, Italy.
Pediatr Emerg Care. 2018 Aug;34(8):545-551. doi: 10.1097/PEC.0000000000000811.
Apparent life-threatening event (ALTE) refers to a constellation of unexpected events suddenly occurring in infants that extremely alarm the observers. The objectives of this study were to evaluate 1) intervention of Emergency Service (ES) at home, 2) parental behavior before ES intervention, 3) patients' outcome at follow-up of a minimum of 6 months.
Retrospective study of infants younger than 12 months whose parents called ES and were evaluated for ALTE from 2005 to 2014. Tactile stimulation (TS) was defined as any maneuver performed by parents or ES staff aimed at rescuing patients without cardiopulmonary resuscitation attempts. Cardiopulmonary resuscitation was defined according to American Heart Association Guidelines 2010.
One hundred eighty-eight patients were eligible. Emergency Service provided intervention for 178 infants (10 were assisted only by phone). All patients received TS by parents before ES arrival. Mean time for ES to reach patient location was 15 ± 10 minutes. On examination, 136 patients (76.5%) seemed normal and 42 symptomatic. One hundred sixty-three patients were brought to the emergency department where 23 patients were found symptomatic. One hundred six of 163 patients underwent capillary blood gas determination and, in 28 (26%) of 106, alterations were found. No infant had subsequent cardiopulmonary arrest or clinically evident adverse neurological outcome. Six were found to be epileptic. No infant died during the episode or during follow-up.
Our findings suggest that ALTE is an alarming but self-limiting phenomenon that can be resolved either spontaneously or by simple TS in most cases. Emergency Service should solicit patients' physiological responses through TS first while considering a cardiopulmonary resuscitation maneuver.
明显危及生命事件(ALTE)指的是突然发生在婴儿身上的一系列意外事件,会让观察者极度惊恐。本研究的目的是评估:1)在家中紧急服务(ES)的干预情况;2)紧急服务干预前家长的行为;3)至少随访6个月时患者的结局。
对2005年至2014年期间家长呼叫紧急服务并接受ALTE评估的12个月以下婴儿进行回顾性研究。触觉刺激(TS)定义为家长或紧急服务人员为抢救患者而进行的任何未尝试心肺复苏的操作。心肺复苏根据美国心脏协会2010年指南进行定义。
188例患者符合条件。紧急服务为178名婴儿提供了干预(10名仅通过电话得到协助)。所有患者在紧急服务到达之前均接受了家长的触觉刺激。紧急服务到达患者所在地的平均时间为15±10分钟。检查时,136例患者(76.5%)看起来正常,42例有症状。163例患者被送往急诊科,其中23例被发现有症状。163例患者中的106例进行了毛细血管血气测定,其中106例中的28例(26%)发现有异常。没有婴儿随后发生心肺骤停或出现临床上明显的不良神经学结局。6例被发现患有癫痫。没有婴儿在事件期间或随访期间死亡。
我们的研究结果表明,ALTE是一种令人惊恐但自限性的现象,在大多数情况下可自发解决或通过简单的触觉刺激解决。紧急服务在考虑进行心肺复苏操作时,应首先通过触觉刺激来探寻患者的生理反应。