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A Sweet Response to a Sour Situation: The Role of Soluble Pattern Recognition Receptors in the Innate Immune Response to Invasive Aspergillus fumigatus Infections.

作者信息

Bidula Stefan, Schelenz Silke

机构信息

Aberdeen Fungal Group, School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.

Department of Microbiology, Royal Brompton Hospital, London, United Kingdom.

出版信息

PLoS Pathog. 2016 Jul 14;12(7):e1005637. doi: 10.1371/journal.ppat.1005637. eCollection 2016 Jul.

DOI:10.1371/journal.ppat.1005637
PMID:27415780
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4945084/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f5c/4945084/b93388dd43de/ppat.1005637.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f5c/4945084/b93388dd43de/ppat.1005637.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f5c/4945084/b93388dd43de/ppat.1005637.g001.jpg

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H-ficolin binds Aspergillus fumigatus leading to activation of the lectin complement pathway and modulation of lung epithelial immune responses.H-纤维胶凝蛋白结合烟曲霉，导致凝集素补体途径激活及肺上皮免疫反应调节。
Immunology. 2015 Oct;146(2):281-91. doi: 10.1111/imm.12501. Epub 2015 Aug 24.
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Stud Mycol. 2021 May 10;100:100115. doi: 10.1016/j.simyco.2021.100115. eCollection 2021 Sep.
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