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系统性红斑狼疮中光敏性的患病率及表达情况

Prevalence and expression of photosensitivity in systemic lupus erythematosus.

作者信息

Wysenbeek A J, Block D A, Fries J F

机构信息

Department of Medicine, Stanford University School of Medicine, California.

出版信息

Ann Rheum Dis. 1989 Jun;48(6):461-3. doi: 10.1136/ard.48.6.461.

Abstract

Photosensitivity was assessed in 125 patients with systemic lupus erythematosus (SLE) and in 281 patients with rheumatoid arthritis (RA) as controls. Photosensitivity was reported by 87/119 (73%) patients with SLE and in 62/269 (23%) patients with RA; involving the face in 72/122 (59%) patients with SLE, then arms, chest, and neck. Patients with SLE reported that sun exposure could exacerbate various systemic symptoms, 51/121 (42%) reported medical treatment for photosensitivity and 41/118 (35%) reported that photosensitivity had a significant impact on their lifestyle. There was no significant difference in disease severity, as judged by physician or laboratory results, between patients scoring high or low on the photosensitivity scale.

摘要

对125例系统性红斑狼疮(SLE)患者和281例类风湿关节炎(RA)患者作为对照进行了光敏性评估。119例SLE患者中有87例(73%)报告有光敏性,269例RA患者中有62例(23%)报告有光敏性;122例SLE患者中有72例(59%)面部受累,其次是手臂、胸部和颈部。SLE患者报告日晒会加重各种全身症状,121例中有51例(42%)报告因光敏性接受过治疗,118例中有41例(35%)报告光敏性对其生活方式有重大影响。根据医生判断或实验室结果,光敏性评分高或低的患者在疾病严重程度上没有显著差异。

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