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用于血栓后综合征的间歇性压迫装置。一项初步研究。

Intermittent compression units for the postphlebitic syndrome. A pilot study.

作者信息

Ginsberg J S, Brill-Edwards P, Kowalchuk G, Hirsh J

机构信息

Department of Medicine, McMaster University, Hamilton, Canada.

出版信息

Arch Intern Med. 1989 Jul;149(7):1651-2.

PMID:2742439
Abstract

The postphlebitic syndrome is a common affliction with limited therapeutic options. Patients who fail to respond to treatment with graded elastic compression stockings often develop a chronic pain syndrome manifested by intractable pain and swelling. Because lymphedema, a condition also associated with leg pain and swelling, has been successfully treated by intermittent compressive therapy with an extremity pump, we conducted a pilot study of compressive therapy in patients with severe postphlebitic syndrome. All five patients studied had dramatic improvement in symptoms and functional status without side effects. Although a large randomized trial is needed to properly evaluate compressive therapy, it appears to be very effective in selected patients.

摘要

血栓形成后综合征是一种常见疾病,治疗选择有限。对分级压力弹力袜治疗无反应的患者常发展为以顽固性疼痛和肿胀为表现的慢性疼痛综合征。由于淋巴水肿(一种也与腿痛和肿胀相关的病症)已通过肢体泵间歇性压迫疗法成功治疗,我们对重度血栓形成后综合征患者进行了压迫疗法的初步研究。所有纳入研究的5例患者症状和功能状态均有显著改善,且无副作用。虽然需要进行大规模随机试验来正确评估压迫疗法,但它在部分患者中似乎非常有效。

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1
Intermittent compression units for the postphlebitic syndrome. A pilot study.用于血栓后综合征的间歇性压迫装置。一项初步研究。
Arch Intern Med. 1989 Jul;149(7):1651-2.
2
Intermittent compression units for severe post-phlebitic syndrome: a randomized crossover study.用于严重静脉炎后综合征的间歇性压迫装置:一项随机交叉研究。
CMAJ. 1999 May 4;160(9):1303-6.
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Evaluation of the effects of elastic compression in patients with postphlebitic limbs by laser-Doppler flowmetry.通过激光多普勒血流仪评估弹性压迫对血栓后肢体患者的影响。
Phlebologie. 1988 Nov-Dec;41(4):797-802.
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Long-term outcomes after deep vein thrombosis: postphlebitic syndrome and quality of life.深静脉血栓形成后的长期结局:血栓后综合征与生活质量
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[Indications-related use of stockings--measuring venous pump function].[与适应症相关的弹力袜使用——测量静脉泵功能]
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引用本文的文献

1
[S1 guideline on intermittent pneumatic compression (IPC)].[间歇性气动压迫(IPC)的S1指南]
Hautarzt. 2018 Aug;69(8):662-673. doi: 10.1007/s00105-018-4219-1.
2
Effectiveness of compression stockings to prevent the post-thrombotic syndrome (the SOX Trial and Bio-SOX biomarker substudy): a randomized controlled trial.压力袜预防血栓形成后综合征的有效性(SOX试验和生物SOX生物标志物子研究):一项随机对照试验。
BMC Cardiovasc Disord. 2007 Jul 24;7:21. doi: 10.1186/1471-2261-7-21.
3
The post-thrombotic syndrome: the forgotten morbidity of deep venous thrombosis.
血栓形成后综合征:深静脉血栓被遗忘的并发症
J Thromb Thrombolysis. 2006 Feb;21(1):41-8. doi: 10.1007/s11239-006-5574-9.
4
Long-term outcomes after deep vein thrombosis: postphlebitic syndrome and quality of life.深静脉血栓形成后的长期结局:血栓后综合征与生活质量
J Gen Intern Med. 2000 Jun;15(6):425-9. doi: 10.1046/j.1525-1497.2000.06419.x.
5
Intermittent compression units for severe post-phlebitic syndrome: a randomized crossover study.用于严重静脉炎后综合征的间歇性压迫装置:一项随机交叉研究。
CMAJ. 1999 May 4;160(9):1303-6.