Ginsberg J S, Brill-Edwards P, Kowalchuk G, Hirsh J
Department of Medicine, McMaster University, Hamilton, Canada.
Arch Intern Med. 1989 Jul;149(7):1651-2.
The postphlebitic syndrome is a common affliction with limited therapeutic options. Patients who fail to respond to treatment with graded elastic compression stockings often develop a chronic pain syndrome manifested by intractable pain and swelling. Because lymphedema, a condition also associated with leg pain and swelling, has been successfully treated by intermittent compressive therapy with an extremity pump, we conducted a pilot study of compressive therapy in patients with severe postphlebitic syndrome. All five patients studied had dramatic improvement in symptoms and functional status without side effects. Although a large randomized trial is needed to properly evaluate compressive therapy, it appears to be very effective in selected patients.
血栓形成后综合征是一种常见疾病,治疗选择有限。对分级压力弹力袜治疗无反应的患者常发展为以顽固性疼痛和肿胀为表现的慢性疼痛综合征。由于淋巴水肿(一种也与腿痛和肿胀相关的病症)已通过肢体泵间歇性压迫疗法成功治疗,我们对重度血栓形成后综合征患者进行了压迫疗法的初步研究。所有纳入研究的5例患者症状和功能状态均有显著改善,且无副作用。虽然需要进行大规模随机试验来正确评估压迫疗法,但它在部分患者中似乎非常有效。