Belcaro G, Grigg M, Vasdekis S, Rulo A, Christopoulos D, Nicolaides A
Irvine Laboratory for Cardiovascular Investigation and Research, St Mary's Hospital Medical School, London, UK.
Phlebologie. 1988 Nov-Dec;41(4):797-802.
Laser-Doppler flowmetry has been used to study the skin microcirculation in 20 normal limbs and 80 limbs of patients with venous hypertension and leg ulceration due to deep venous reflux. It was found that limbs with venous hypertension had a high skin resting blood flow (BRF) and an impaired veno-arteriolar reflex (VR). There was a marked improvement in both BRF and VR after elastic compression for three weeks and an association between this improvement and the rate of healing of the leg ulcers. The results indicate that elastic compression may affect the microcirculation even though it does not alter the venous pressure measurements when the elastic stockings are removed.
激光多普勒血流仪已被用于研究20条正常肢体以及80条因深静脉反流导致静脉高压和腿部溃疡患者的肢体的皮肤微循环。研究发现,患有静脉高压的肢体皮肤静息血流量(BRF)较高,且静脉-小动脉反射(VR)受损。经过三周的弹性压迫后,BRF和VR均有显著改善,且这种改善与腿部溃疡的愈合速度相关。结果表明,即使去除弹性长袜后弹性压迫并未改变静脉压力测量值,但它可能会影响微循环。