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鞘内注射荧光素在人工耳蜗植入后复发性脑膜炎中的应用

Use of Intrathecal Fluorescein in Recurrent Meningitis after Cochlear Implantation.

作者信息

Tandon Swati, Singh Satinder, Sharma Shalabh, Lahiri Asish K

机构信息

Department of Otorhinolaryngology, Sir Ganga Ram Hospital, Delhi, India.

Deputy Director, Cochlear Implant Services, Sir Ganga Ram Hospital Delhi, India.

出版信息

Iran J Otorhinolaryngol. 2016 May;28(86):221-6.

PMID:27429952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4930846/
Abstract

INTRODUCTION

Congenital anomalies of the cochlea and labyrinth can be associated with meningitis and varying degrees of hearing loss or deafness. Despite antibiotics, meningitis remains a life threatening complication.

CASE REPORT

We report a case of recurrent meningitis following episodes of otitis media in a cochlear implantee child with bilateral vestibulocochlear malformation, due to fistula in the stapes footplate. Intrathecal fluorescin was used to identify the leak site.

CONCLUSION

Recurrent meningitis can indicate for possible immunological or anatomical abnormalities as well for chronic parameningeal infections. Intraoperative use of intrathecal fluorescin is an ideal investigative tool to demonstrate cerebrospinal fluid (CSF) leak site in patients in whom other investigations fail to do so.

摘要

引言

耳蜗和迷路的先天性异常可能与脑膜炎以及不同程度的听力损失或耳聋有关。尽管使用了抗生素,脑膜炎仍然是一种危及生命的并发症。

病例报告

我们报告了一例人工耳蜗植入儿童的复发性脑膜炎病例,该儿童双侧前庭蜗畸形,因镫骨足板瘘管导致中耳炎发作。鞘内注射荧光素用于确定渗漏部位。

结论

复发性脑膜炎可能提示存在免疫或解剖学异常以及慢性脑膜旁感染。在其他检查无法确定脑脊液(CSF)渗漏部位的患者中,术中使用鞘内荧光素是一种理想的检查工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be1/4930846/485d73e66f09/ijo-28-221-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be1/4930846/b2975e022df3/ijo-28-221-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be1/4930846/485d73e66f09/ijo-28-221-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be1/4930846/b2975e022df3/ijo-28-221-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be1/4930846/485d73e66f09/ijo-28-221-g002.jpg

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本文引用的文献

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Differentiation between CSF Otorrhea and Rhinorrhea in an Obscure Case of Recurrent Meningitis.复发性脑膜炎疑难病例中脑脊液耳漏与鼻漏的鉴别
Iran J Otorhinolaryngol. 2014 Apr;26(75):119-23.
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Italian multicentre study on intrathecal fluorescein for craniosinusal fistulae.意大利关于鞘内注射荧光素用于颅窦瘘的多中心研究。
Acta Otorhinolaryngol Ital. 2008 Aug;28(4):159-63.
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Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis.复发性细菌性脑膜炎的流行病学、病因学、发病机制及诊断
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A new classification for cochleovestibular malformations.一种新的耳蜗前庭畸形分类法。
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Mondini dysplasia of the inner ear with CSF leak-A rare cause of recurrent meningitis.伴有脑脊液漏的内耳Mondini发育异常——复发性脑膜炎的罕见病因
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Cochlear implantation in children with inner ear malformations.内耳畸形儿童的人工耳蜗植入
Ann Otol Rhinol Laryngol. 1998 Jun;107(6):492-500. doi: 10.1177/000348949810700607.
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Meningitis after cochlear implantation in Mondini malformation.Mondini畸形人工耳蜗植入术后的脑膜炎
Otolaryngol Head Neck Surg. 1997 Jan;116(1):104-6. doi: 10.1016/S0194-59989770358-9.
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