Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Department of Dermatology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
Sci Rep. 2016 Jul 19;6:29751. doi: 10.1038/srep29751.
Prevalence of atopic dermatitis (AD) is increasing worldwide. Up to date, there has been no face-to-face nation-wide study in China. We aim to explore the prevalence of clinical diagnosed AD in children aged 1-7 ys in China. Twelve metropolises were chosen from different areas of China. In each region, we selected 4-10 kindergartens and 2-5 vaccination clinics randomly. A complete history-taking and skin examination were performed by dermatologists. The definite diagnosis of AD and the severity were determined by two or three dermatologists. All criteria concerned in UK diagnosis criteria, characteristic presentation of AD and atypical manifestations were recorded in detail. A total of 13998 children from 84 kindergartens and 40 vaccination clinics were included. The prevalence of AD was 12.94% by clinical diagnosis of dermatologists overall, with 74.6% of mild AD. Comparatively, prevalence of AD based on UK diagnostic criteria was 4.76%. This is the first face-to-face nation-wide study in Chinese children aged 1-7 ys, revealing that the prevalence of AD in children is closer to that of wealthier nations.
特应性皮炎（AD）的患病率在全球范围内呈上升趋势。迄今为止，中国还没有进行过全国范围的面对面研究。我们旨在探讨中国 1-7 岁儿童临床诊断 AD 的患病率。我们从中国不同地区选择了 12 个大都市。在每个地区，我们随机选择了 4-10 所幼儿园和 2-5 个疫苗接种诊所。皮肤科医生对每位儿童进行了详细的病史询问和皮肤检查。AD 的明确诊断和严重程度由两名或三名皮肤科医生确定。所有标准均参照英国诊断标准、AD 的特征性表现和非典型表现进行详细记录。共有来自 84 所幼儿园和 40 个疫苗接种诊所的 13998 名儿童纳入研究。总体而言，皮肤科医生临床诊断 AD 的患病率为 12.94%，其中 74.6%为轻度 AD。相比之下，根据英国诊断标准，AD 的患病率为 4.76%。这是中国 1-7 岁儿童首次面对面的全国性研究，表明中国儿童 AD 的患病率更接近富裕国家。
