Lydon J
Cancer Nurs. 1989 Jun;12(3):133-43.
With foresight, knowledge, and an awareness of the problem, nephrotoxicity associated with chemotherapy can be prevented or minimized, thereby avoiding irreversible renal failure or death. Careful assessment of those patients at risk for renal damage and the identification of early signs/symptoms of renal impairment are key steps in the prevention and early detection of renal dysfunction. The purpose of this article is to describe the clinical and laboratory manifestations of renal toxicity, as well as the nurse's role in the assessment of nephrotoxicity.
凭借前瞻性、知识以及对该问题的认识,与化疗相关的肾毒性可以得到预防或降至最低,从而避免不可逆转的肾衰竭或死亡。仔细评估那些有肾损伤风险的患者以及识别肾功能损害的早期体征/症状是预防和早期发现肾功能障碍的关键步骤。本文的目的是描述肾毒性的临床和实验室表现,以及护士在肾毒性评估中的作用。