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不同手术技术对腹腔镜袖状胃切除术结局的影响:来自代谢和减重手术认证和质量改进计划(MBSAQIP)的首次报告。

The Impact of Different Surgical Techniques on Outcomes in Laparoscopic Sleeve Gastrectomies: The First Report from the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP).

机构信息

*Loyola University Chicago Stritch School of Medicine, Chicago, IL †Vanderbilt University Medical Center, Nashville, TM ‡Stanford University Medical Center, Stanford, CA §Division of Research and Optimal Patient Care, American College of Surgeons, Chicago, IL American College of Surgeons, Chicago, IL ||Oregon Health and Science University, Portland, OR ¶University of California, Irvine School of Medicine, Irvine, CA #University of California Los Angeles David Geffen School of Medicine, Los Angeles, CA **Department of Surgery, Massachusetts General Hospital, Boston, MA.

出版信息

Ann Surg. 2016 Sep;264(3):464-73. doi: 10.1097/SLA.0000000000001851.

Abstract

OBJECTIVE

Questions remain regarding best surgical techniques to use for a laparoscopic sleeve gastrectomy (LSG) including the use of staple line reinforcement (SLR), bougie size (BS), and distance from the pylorus (DP) where the staple line is initiated. Our objectives were to assess the impact of these techniques on 30-day outcomes and to evaluate the impact of these techniques on weight loss and comorbidities at 1 year.

METHODS

Using the MBSAQIP data registry, univariate analyses and hierarchical logistical regression models were developed to analyze outcomes for techniques of LSG at patient and surgeon-level.

RESULTS

A total of 189,477 LSG operations were performed by 1634 surgeons at 720 centers from 2012 to 2014. Eighty percent of surgeons used SLR, 20% did not. SLR cases were associated with higher leak rates (0.96% vs 0.65%, odds ratio [OR] 1.20 95% confidence interval [CI] 1.00-1.43) and lower bleed rates (0.75% vs 1.00%, OR 0.74 95% CI 0.63-0.86) compared to no SLR at patient level. At the surgeon level, leak rates remained significant, but bleeding events became nonsignificant. BS ≥38 was associated with significantly lower leak rates compared to BS <38 at patient and surgeon level (patient level: 0.80% vs 0.96%, OR 0.72, 95% CI 0.62-0.94; surgeon level: 0.84% vs 0.95%, OR 0.90, 95% CI 0.80-0.99). BS ≥40 was associated with increased weight loss. DP had no impact on leaks or bleeds but showed an increase in weight loss with increasing DP.

CONCLUSION

LSG is a safe procedure with a low morbidity rate. SLR is associated with increased leak rates. A surgeon should consider risks, benefits, and costs of these surgical techniques when performing a LSG and selectively utilize those that, in their hands, minimize morbidity while maximizing clinical effectiveness.

摘要

目的

腹腔镜袖状胃切除术(LSG)的最佳手术技术仍存在争议,包括使用吻合线加固(SLR)、胃管尺寸(BS)和吻合线起始处的幽门距离(DP)。我们的目的是评估这些技术对 30 天结果的影响,并评估这些技术对 1 年时体重减轻和合并症的影响。

方法

使用 MBSAQIP 数据登记处,对患者和外科医生层面的 LSG 技术进行单变量分析和分层逻辑回归模型分析。

结果

2012 年至 2014 年,共有 1634 名外科医生在 720 家中心进行了 189477 例 LSG 手术。80%的外科医生使用 SLR,20%的外科医生不使用 SLR。与未使用 SLR 相比,使用 SLR 的病例吻合口漏的发生率更高(0.96%比 0.65%,比值比[OR]1.20,95%置信区间[CI]1.00-1.43),出血发生率更低(0.75%比 1.00%,OR 0.74,95%CI 0.63-0.86)。在外科医生层面,吻合口漏的发生率仍然显著,但出血事件变得不显著。BS≥38 与 BS<38 相比,患者和外科医生层面的吻合口漏发生率显著降低(患者层面:0.80%比 0.96%,OR 0.72,95%CI 0.62-0.94;外科医生层面:0.84%比 0.95%,OR 0.90,95%CI 0.80-0.99)。BS≥40 与体重减轻增加相关。DP 对漏诊或出血无影响,但随着 DP 的增加,体重减轻增加。

结论

LSG 是一种安全的手术,发病率低。SLR 与吻合口漏的发生率增加有关。外科医生在进行 LSG 时应考虑这些手术技术的风险、益处和成本,并选择性地使用那些在他们手中能将发病率降到最低同时最大限度地提高临床效果的技术。

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