雄性大鼠青春期前副嗅球发育的激素调控

Prepubescent hormonal control of the development of accessory olfactory bulbs in the male rat.

作者信息

Roos J, Roos M, Schaeffer C, Aron C

机构信息

Institute of Histology, Faculty of Medicine, Strasbourg, France.

出版信息

Brain Res Dev Brain Res. 1989 Jun 1;47(2):309-12. doi: 10.1016/0165-3806(89)90188-0.

DOI:10.1016/0165-3806(89)90188-0

PMID:2743563

Abstract

The effects of androgen treatment (TP) from postnatal day 20 (P20) onwards on the accessory olfactory bulbs' (AOB) development were studied in rats orchidectomized at birth (PO) or on P20. TP failed to restore impaired AOB development in the rats castrated at PO but completely restored AOB development in those castrated at P20. Androgen secretion during both the perinatal and prepubescent periods appeared to be critical for male AOB development.

摘要

研究了从出生后第20天（P20）起雄激素处理（TP）对出生时（PO）或P20时去势大鼠副嗅球（AOB）发育的影响。TP未能恢复出生时去势大鼠受损的AOB发育，但完全恢复了P20时去势大鼠的AOB发育。围产期和青春期前的雄激素分泌似乎对雄性AOB发育至关重要。