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吲哚菁绿辅助机器人胆囊切除术能否降低腹腔镜手术中转开腹的发生率?最大规模单机构研究的直接比较。

Could ICG-aided robotic cholecystectomy reduce the rate of open conversion reported with laparoscopic approach? A head to head comparison of the largest single institution studies.

作者信息

Gangemi A, Danilkowicz R, Elli F E, Bianco F, Masrur M, Giulianotti P C

机构信息

Division of General, Minimally Invasive and Robotic Surgery, University of Illinois at Chicago, 840 S. Wood Street, Suite 435E, Chicago, IL, 60612, USA.

出版信息

J Robot Surg. 2017 Mar;11(1):77-82. doi: 10.1007/s11701-016-0624-6. Epub 2016 Jul 19.

Abstract

Comparative studies between robotic and laparoscopic cholecystectomy (LC) focus heavily on economic considerations under the assumption of comparable clinical outcomes. Advancement of the robotic technique and the further widespread use of this approach suggest a need for newer comparison studies. 676 ICG-aided robotic cholecystectomies (ICG-aided RC) performed at the University of Illinois at Chicago (UIC) Division of General, Minimally Invasive and Robotic Surgery were compiled retrospectively. Additionally, 289 LC were similarly obtained. Data were compared to the largest single institution LC data sets from within the US and abroad. Statistically significant variations were found between UIC-RC and UIC-LC in minor biliary injuries (p = 0.049), overall open conversion (p ≤ 0.001), open conversion in the acute setting (p = 0.002), and mean blood loss (p < 0.001). UIC-RC open conversions were also significantly lower than Greenville Health System LC (p ≤ 0.001). Additionally, UIC ICG-RC resulted in the lowest percentages of major biliary injuries (0 %) and highest percentage of biliary anomalies identified (2.07 %). ICG-aided cholangiography and the technical advantages associated with the robotic platform may significantly decrease the rate of open conversion in both the acute and non-acute setting. The sample size discrepancy and the non-randomized nature of our study do not allow for drawing definitive conclusions.

摘要

机器人辅助与腹腔镜胆囊切除术(LC)的比较研究在假定临床结果可比的情况下,严重侧重于经济考量。机器人技术的进步以及该方法的进一步广泛应用表明需要开展更新的比较研究。对芝加哥伊利诺伊大学(UIC)普通、微创和机器人手术科进行的676例吲哚菁绿(ICG)辅助机器人胆囊切除术(ICG辅助RC)进行了回顾性汇编。此外,类似地获取了289例LC的数据。将这些数据与美国国内外最大的单机构LC数据集进行了比较。发现UIC-RC与UIC-LC在轻微胆管损伤(p = 0.049)、总体中转开腹(p≤0.001)、急性情况下的中转开腹(p = 0.002)以及平均失血量(p < 0.001)方面存在统计学显著差异。UIC-RC的中转开腹率也显著低于格林维尔健康系统的LC(p≤0.001)。此外,UIC的ICG-RC导致主要胆管损伤的百分比最低(0%),而识别出的胆管异常百分比最高(2.07%)。ICG辅助胆管造影以及与机器人平台相关的技术优势可能会显著降低急性和非急性情况下的中转开腹率。我们研究的样本量差异和非随机性质不允许得出明确结论。

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