Blok C G H, de Ridder M A J, Verhamme K M C, Moorman P W
Department of Medical Informatics, Erasmus Medical Centre, P.O. Box 2040, 3015 CA, Rotterdam, The Netherlands.
BMC Geriatr. 2016 Jul 19;16:142. doi: 10.1186/s12877-016-0316-0.
It is unknown to what extent General Practitioners (GPs) manage hypertension (HT) differently in older patients, as compared to younger age groups. The purpose of our study was to compare HT management in older patients to younger age groups.
We performed a retrospective cohort study of patients of 159 GP's practices in the Integrated Primary Care Information (IPCI) database. The study period lasted from September 2010 through December 2012. The study population consisted of all patients aged 60 years or older with at least one blood pressure (BP) measurement during the inclusion period, without pre-existent HT, diabetes mellitus (DM) or atherosclerotic cardiovascular disease at time of study start. Study outcomes were a diagnosis of HT within one month after cohort entry and the use of antihypertensive medication within 4 months after cohort entry in HT diagnosed patients. We compared the incidence of outcomes between the age groups, stratified by systolic blood pressure (SBP). Logistic regression analysis was used to assess the influence of age-adjusted SBP Z-scores, age and gender on the outcomes.
We included 19,500 patients from 159 GP's practices of whom 1,181 (6.1 %) were newly diagnosed with HT. Corrected for age-adjusted SBP, older patients were less likely to be diagnosed with HT (odds ratio per year age increase 0.98, p < 0.001). Corrected for age-adjusted SBP, no significant effect of age on the probability of treatment in newly diagnosed HT patients was observed (p = 0.82).
This study showed that GPs are less inclined to diagnose HT with increasing patient age, but do not withhold treatment when they diagnose HT in older patients.
与年轻患者相比,全科医生(GP)在老年患者中管理高血压(HT)的方式存在多大差异尚不清楚。我们研究的目的是比较老年患者与年轻患者的高血压管理情况。
我们对综合初级保健信息(IPCI)数据库中159家全科医生诊所的患者进行了一项回顾性队列研究。研究期从2010年9月持续到2012年12月。研究人群包括所有年龄在60岁及以上、在纳入期内至少有一次血压(BP)测量、研究开始时无既往高血压、糖尿病(DM)或动脉粥样硬化性心血管疾病的患者。研究结果是队列入组后1个月内高血压诊断以及高血压诊断患者队列入组后4个月内使用抗高血压药物。我们比较了按收缩压(SBP)分层的各年龄组间结果的发生率。采用逻辑回归分析评估年龄调整后的SBP Z评分、年龄和性别对结果的影响。
我们纳入了来自159家全科医生诊所的19500名患者,其中1181名(6.1%)新诊断为高血压。校正年龄调整后的SBP后,老年患者被诊断为高血压的可能性较小(每年年龄增加的优势比为0.98,p<0.001)。校正年龄调整后的SBP后,未观察到年龄对新诊断高血压患者治疗概率有显著影响(p=0.82)。
本研究表明,全科医生诊断高血压的倾向随患者年龄增加而降低,但在诊断老年患者高血压时并不停止治疗。