Bilal Muhammad, Haseeb Abdul, Khan Mohammad Hassaan, Arshad Mohammad Hussham, Ladak Asma Akbar, Niazi Sufyan Khan, Musharraf Muhammad Daniyal, Manji Adil Al-Karim
Faculty, Department of Medicine, Dow Medical College. Dow University of Health Sciences , Karachi, Pakistan .
Faculty, Department of Medicine, Dow Medical College, Dow University of Health Sciences , Karachi, Pakistan .
J Clin Diagn Res. 2016 May;10(5):OC08-13. doi: 10.7860/JCDR/2016/18294.7730. Epub 2016 May 1.
Self-medication with antibiotics is becoming increasingly common due to multiple factors. The public who are using these antibiotics generally do not have full information regarding their proper use, especially the dosages and possible side-effects. Hence, unregulated use of such medicines may cause dangerous adverse effects in the patients.
The study was aimed to evaluate the prevalence and practice of self-medication with antibiotics among people dwelling in the rural areas of province Sindh.
A cross-sectional survey was performed at Outpatient Department of Civil Hospital Karachi, from January to March 2015. Four hundred rural dwellers who lived in the outskirts of Karachi city area of province Sindh were recruited for the study in the aforementioned time period through non-probability convenience sampling.
The investigation reported a prevalence of 81.25% among rural dwellers of Sindh with regards to self-medication of antibiotics. The most common reason behind self-medication were economic reasons (88.0%). Amoxicillin (52.0%) was found to be the most self-prescribed antibiotic. Majority of the participants (74.7%) didn't know about the phenomena of antibiotic resistance associated with inadequate use of antibiotics and only 25 subjects identified correctly that the situation would lead to increase resistance.
The self-medication rates with antibiotic are higher in rural areas of Sindh. There is an urgent need for the government to enforce stricter laws on pharmacies dispensing medications, especially antibiotics, without prescriptions. Lastly, provision of cost effective treatment from public sector can significantly reduce self-medication with antibiotics among rural dwellers of Sindh.
由于多种因素，抗生素自我药疗正变得越来越普遍。使用这些抗生素的公众通常没有关于其正确使用的完整信息，尤其是剂量和可能的副作用。因此，无节制地使用此类药物可能会给患者带来危险的不良反应。
本研究旨在评估信德省农村地区居民抗生素自我药疗的流行情况和实践。
2015年1月至3月在卡拉奇市民医院门诊部进行了一项横断面调查。通过非概率便利抽样，在上述时间段招募了400名居住在信德省卡拉奇市郊区的农村居民参与研究。
调查显示，信德省农村居民中抗生素自我药疗的流行率为81.25%。自我药疗最常见的原因是经济原因（88.0%）。阿莫西林（52.0%）是最常自我开具的抗生素。大多数参与者（74.7%）不知道与抗生素使用不当相关的抗生素耐药现象，只有25名受试者正确认识到这种情况会导致耐药性增加。
信德省农村地区抗生素自我药疗率较高。政府迫切需要对无处方配药的药店，尤其是抗生素配药，实施更严格的法律。最后，公共部门提供具有成本效益的治疗可以显著减少信德省农村居民的抗生素自我药疗。
