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暴露于细颗粒物与因肺炎住院:对住院人数及其费用的影响。

Exposure to fine particulate matter and hospital admissions due to pneumonia: Effects on the number of hospital admissions and its costs.

作者信息

Patto Nicole Vargas, Nascimento Luiz Fernando Costa, Mantovani Katia Cristina C, Vieira Luciana C P F S, Moreira Demerval S

机构信息

Medical Student, Universidade de Taubaté (Unitau), Taubaté, SP, Brazil.

PhD, Department of Medicine, Unitau, Taubaté, SP, Brazil.

出版信息

Rev Assoc Med Bras (1992). 2016 Jul;62(4):342-6. doi: 10.1590/1806-9282.62.04.342.

Abstract

OBJECTIVE

Given that respiratory diseases are a major cause of hospitalization in children, the objectives of this study are to estimate the role of exposure to fine particulate matter in hospitalizations due to pneumonia and a possible reduction in the number of these hospitalizations and costs.

METHOD

An ecological time-series study was developed with data on hospitalization for pneumonia among children under 10 years of age living in São José do Rio Preto, state of São Paulo, using PM2.5 concentrations estimated using a mathematical model. We used Poisson regression with a dependent variable (hospitalization) associated with PM2.5 concentrations and adjusted for effective temperature, seasonality and day of the week, with estimates of reductions in the number of hospitalizations and costs.

RESULTS

1,161 children were admitted to hospital between October 1st, 2011, and September 30th, 2013; the average concentration of PM2.5 was 18.7 µg/m3 (≈32 µg/m3 of PM10) and exposure to this pollutant was associated with hospitalization four and five days after exposure.

CONCLUSION

A 10 µg/m3 decrease in concentration would imply 256 less hospital admissions and savings of approximately R$ 220,000 in a medium-sized city.

摘要

目的

鉴于呼吸道疾病是儿童住院的主要原因,本研究的目的是评估接触细颗粒物在肺炎住院病例中的作用,以及这种住院病例数量和费用可能的减少情况。

方法

开展了一项生态时间序列研究,利用数学模型估算的PM2.5浓度数据,对圣保罗州里奥普雷图河畔圣若泽市10岁以下儿童的肺炎住院情况进行分析。我们使用泊松回归分析,将因变量(住院情况)与PM2.5浓度相关联,并对有效温度、季节性和星期几进行调整,同时估算住院病例数量和费用的减少情况。

结果

2011年10月1日至2013年9月30日期间,1161名儿童住院;PM2.5的平均浓度为18.7微克/立方米(约相当于32微克/立方米的PM10),接触这种污染物与接触后四至五天的住院情况相关。

结论

在一个中等规模城市中,浓度每降低10微克/立方米将意味着少256例住院病例,并节省约22万雷亚尔。

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