MD, PhD. Researcher, Postgraduate Program on Mechanical Engineering, Department of Energy, Universidade Estadual de São Paulo (UNESP), Guaratinguetá, Brazil.
MSc. Doctoral Student, Postgraduate Program on Mechanical Engineering, Department of Energy, Universidade Estadual de São Paulo (UNESP), Guaratinguetá, Brazil.
Sao Paulo Med J. 2021 Oct 29;139(6):591-597. doi: 10.1590/1516-3180.2021.0129.090422021. eCollection 2021.
Exposure to air pollutants is associated with hospital admissions due to cardiovascular diseases and premature deaths.
To estimate years of life lost (YLL) due to premature deaths and their financial costs.
Ecological time-series study carried out in São José dos Campos, Brazil, in 2016.
Data on deaths among residents of this city in 2016 were assessed to estimate the financial cost of premature deaths associated with air pollution. The diagnoses studied were ischemic heart disease, congestive heart failure and cerebrovascular disease, according to YLL. The fractions attributable to deaths associated with air pollutant exposure and to each potential year of life lost were calculated using negative binomial regression with lags of 0-7 days between exposure and outcome. Nitrogen dioxide, particulate matter (PM10) and ozone concentrations were included in the model and adjusted for temperature, humidity and seasonality.
Exposure to particulate matter was significant at lag 3 days. There were 2177 hospitalizations over the study period, with 201 deaths (9.2%). Premature deaths led to 2035.69 years of life lost. A 10 μg/m3 increase in PM10 concentrations was correlated with 8.0% of the hospitalizations, which corresponded to 152.67 YLL (81.67 for males and 71.00 for females). The cost generated was approximately US$ 9.1 million in 2016.
In this first study conducted in a medium-sized Brazilian city, using the YLL methodology, we identified an excess expense attributable to air pollution.
暴露于空气污染物与心血管疾病导致的住院和过早死亡有关。
评估因过早死亡导致的生命年损失（YLL）及其经济成本。
在巴西圣若泽·多斯坎波斯进行的生态时间序列研究，于 2016 年进行。
评估该市 2016 年居民死亡数据，以估算与空气污染相关的过早死亡的经济成本。根据 YLL，研究的诊断包括缺血性心脏病、充血性心力衰竭和脑血管疾病。使用具有 0-7 天暴露-结果滞后的负二项回归计算归因于空气污染物暴露的死亡比例和每个潜在生命年损失的比例。将二氧化氮、颗粒物（PM10）和臭氧浓度纳入模型，并根据温度、湿度和季节性进行调整。
暴露于颗粒物在第 3 天滞后时具有统计学意义。研究期间共有 2177 例住院，201 例死亡（9.2%）。过早死亡导致 2035.69 年的生命年损失。PM10 浓度增加 10μg/m3 与 8.0%的住院相关，相当于 152.67 年 YLL（男性为 81.67 年，女性为 71.00 年）。2016 年产生的费用约为 910 万美元。
在这项在巴西中型城市进行的首次研究中，我们使用 YLL 方法确定了归因于空气污染的超额支出。
