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美国心血管死亡率的最新趋势和公共卫生目标。

Recent Trends in Cardiovascular Mortality in the United States and Public Health Goals.

机构信息

Division of Research, Kaiser Permanente Northern California, Oakland.

Department of Endocrinology, Kaiser Permanente Northern California, South San Francisco.

出版信息

JAMA Cardiol. 2016 Aug 1;1(5):594-9. doi: 10.1001/jamacardio.2016.1326.

Abstract

IMPORTANCE

Heart disease (HD) and cancer are the 2 leading causes of death in the United States. During the first decade of the 21st century, HD mortality declined at a much greater rate than cancer mortality and it appeared that cancer would overtake HD as the leading cause of death.

OBJECTIVES

To determine whether changes in national trends had occurred in recent years in mortality rates due to all cardiovascular disease (CVD), HD, stroke, and cancer and to evaluate the gap between mortality rates from HD and cancer.

DESIGN, SETTING, AND PARTICIPANTS: The Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research data system was used to determine national trends in age-adjusted mortality rates due to all CVD, HD, stroke, and cancer from January 1, 2000, to December 31, 2011, and January 1, 2011, to December 31, 2014, overall, by sex, and by race/ethnicity. The present study was conducted from December 30, 2105, to January 18, 2016.

MAIN OUTCOMES AND MEASURES

Comparison of annual rates of change and trend in gap between HD and cancer mortality rates.

RESULTS

The rate of the decline in all CVD, HD, and stroke mortality decelerated substantially after 2011, and the rate of decline for cancer mortality remained relatively stable. Reported as percentage (95% CI), the annual rates of decline for 2000-2011 were 3.79% (3.61% to 3.97%), 3.69% (3.51% to 3.87%), 4.53% (4.34% to 4.72%), and 1.49% (1.37% to 1.60%) for all CVD, HD, stroke, and cancer mortality, respectively; the rates for 2011-2014 were 0.65% (-0.18% to 1.47%), 0.76% (-0.06% to 1.58%), 0.37% (-0.53% to 1.27%), and 1.55% (1.07% to 2.04%), respectively. Deceleration of the decline in all CVD mortality rates occurred in males, females, and all race/ethnicity groups. For example, the annual rates of decline for total CVD mortality for 2000-2011 were 3.69% (3.48% to 3.89%) for males and 3.98% (3.81% to 4.14%) for females; for 2011-2014, the rates were 0.23% (-0.71% to 1.16%) and 1.17% (0.41% to 1.93%), respectively. The gap between HD and cancer mortality persisted.

CONCLUSIONS AND RELEVANCE

Deceleration in the decline of all CVD, HD, and stroke mortality rates has occurred since 2011. If this trend continues, strategic goals for lowering the burden of CVD set by the American Heart Association and the Million Hearts Initiative may not be reached.

摘要

重要性

心脏病(HD)和癌症是美国的两个主要死亡原因。在 21 世纪的头十年,HD 死亡率的下降速度远远超过癌症死亡率,而且癌症似乎将超过 HD 成为主要的死亡原因。

目的

确定近年来心血管疾病(CVD)、HD、中风和癌症死亡率的全国趋势是否发生了变化,并评估 HD 和癌症死亡率之间的差距。

设计、地点和参与者:使用疾病控制与预防中心广泛在线流行病学研究数据系统,确定 2000 年 1 月 1 日至 2011 年 12 月 31 日和 2011 年 1 月 1 日至 2014 年 12 月 31 日,全国心血管疾病、HD、中风和癌症死亡率的年龄调整率,总体而言,按性别和种族/族裔进行分析。本研究于 2015 年 12 月 30 日至 2016 年 1 月 18 日进行。

主要结果和措施

比较 HD 和癌症死亡率之间差距的年度变化率和趋势。

结果

自 2011 年以来,所有 CVD、HD 和中风死亡率下降的速度明显放缓,而癌症死亡率的下降速度保持相对稳定。以百分比(95%CI)表示,2000-2011 年的年下降率分别为 3.79%(3.61%-3.97%)、3.69%(3.51%-3.87%)、4.53%(4.34%-4.72%)和 1.49%(1.37%-1.60%),分别为 CVD、HD、中风和癌症死亡率;2011-2014 年的年下降率分别为 0.65%(-0.18%-1.47%)、0.76%(-0.06%-1.58%)、0.37%(-0.53%-1.27%)和 1.55%(1.07%-2.04%)。所有 CVD 死亡率下降速度的放缓发生在男性、女性和所有种族/族裔群体中。例如,2000-2011 年男性总 CVD 死亡率的年下降率为 3.69%(3.48%-3.89%),女性为 3.98%(3.81%-4.14%);2011-2014 年,这一比例分别为 0.23%(-0.71%-1.16%)和 1.17%(0.41%-1.93%)。HD 和癌症死亡率之间的差距仍然存在。

结论和相关性

自 2011 年以来,所有 CVD、HD 和中风死亡率下降速度的放缓已经发生。如果这种趋势持续下去,美国心脏协会和百万心脏倡议制定的降低 CVD 负担的战略目标可能无法实现。

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