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美国人口老龄化与 2011 至 2017 年心脏病死亡率的关系。

Association Between Aging of the US Population and Heart Disease Mortality From 2011 to 2017.

机构信息

Division of Research, Kaiser Permanente Northern California, Oakland.

Department of Epidemiology, University of California, San Francisco.

出版信息

JAMA Cardiol. 2019 Dec 1;4(12):1280-1286. doi: 10.1001/jamacardio.2019.4187.

Abstract

IMPORTANCE

A deceleration in the rate of decrease of heart disease (HD) mortality between 2011 and 2014 has been reported. In the context of the rapid increase in the population of adults aged 65 years and older, extending the examination of HD mortality through 2017 has potentially important implications for public health and medical care.

OBJECTIVE

To examine changes in the age-adjusted mortality rate and the number of deaths within subcategories of HD from 2011 to 2017 in conjunction with the change in the size of the US population during the same period.

DESIGN, SETTING, AND PARTICIPANTS: In this quality improvement study, the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) data set was used to identify national changes in the US population aged 65 years and older and in the age-adjusted mortality rates and number of deaths that were listed with an underlying cause of HD, coronary heart disease (CHD), heart failure, and other HDs from January 1, 2011, to December 31, 2017.

MAIN OUTCOMES AND MEASURES

Changes from 2011 to 2017 in the US population and in age-adjusted mortality rates and number of deaths that were listed with an underlying cause of HD, CHD, heart failure (both as an underlying and a contributing cause), and other HDs overall, by sex and race/ethnicity.

RESULTS

The total size of this population of US adults aged 65 years and older increased 22.9% from 41.4 million to 50.9 million between January 1, 2011, and December 31, 2017, while the population of adults younger than 65 years increased by only 1.7%. During this period, the age-adjusted mortality rate decreased 5.0% for HD and 14.9% for CHD while increasing 20.7% for heart failure and 8.4% for other HDs. The number of deaths increased 8.5% for HD, 38.0% for heart failure, and 23.4% for other HDs while decreasing 2.5% for CHD. A total of 80% of HD deaths occurred in the group of adults aged 65 years and older.

CONCLUSIONS AND RELEVANCE

The substantial increase in the growth rate of the group of adults aged 65 years and older who have the highest risk of HD was associated with an increase in the number of HD deaths in this group despite a slowly declining HD mortality rate in the general population. With the number of adults aged 65 years and older projected to increase an additional 44% from 2017 to 2030, innovative and effective approaches to prevent and treat HD, particularly the substantially increasing rates of heart failure, are needed.

摘要

重要性

据报道,2011 年至 2014 年期间,心脏病(HD)死亡率的下降速度有所放缓。在 65 岁及以上成年人人口迅速增加的背景下,将 HD 死亡率的检查延长至 2017 年,对公共卫生和医疗保健具有重要意义。

目的

本质量改进研究使用疾病控制和预防中心广域在线流行病学研究(CDC WONDER)数据集,结合同期美国人口的变化,研究 2011 年至 2017 年期间,65 岁及以上人群的年龄调整死亡率和与 HD、冠心病(CHD)、心力衰竭(均为根本原因和促成原因)以及其他 HD 相关的死亡人数的变化。

设计、设置和参与者:本研究使用疾病控制和预防中心广域在线数据资源(CDC WONDER)数据库,对 2011 年 1 月 1 日至 2017 年 12 月 31 日期间美国 65 岁及以上人群的全国性变化,以及年龄调整死亡率和与 HD、CHD、心力衰竭(均为根本原因和促成原因)以及其他 HD 相关的死亡人数进行了分析。

主要结果和措施

按性别和种族/民族划分,2011 年至 2017 年期间,美国 65 岁及以上人群的总体变化,以及与 HD、CHD、心力衰竭(均为根本原因和促成原因)和其他 HD 相关的年龄调整死亡率和死亡人数的变化。

结果

2011 年至 2017 年期间,美国 65 岁及以上成年人的总人口增加了 22.9%,从 4140 万增至 5090 万,而 65 岁以下成年人的人口仅增长了 1.7%。在此期间,HD 的年龄调整死亡率下降了 5.0%,CHD 的年龄调整死亡率下降了 14.9%,而心力衰竭的年龄调整死亡率上升了 20.7%,其他 HD 的年龄调整死亡率上升了 8.4%。HD 的死亡人数增加了 8.5%,心力衰竭的死亡人数增加了 38.0%,其他 HD 的死亡人数增加了 23.4%,而 CHD 的死亡人数减少了 2.5%。HD 死亡人数的 80%发生在 65 岁及以上的人群中。

结论和相关性

尽管一般人群的 HD 死亡率缓慢下降,但 65 岁及以上人群增长率的大幅上升与该人群 HD 死亡人数的增加有关。预计到 2030 年,65 岁及以上成年人的数量将再增加 44%,因此需要创新和有效的方法来预防和治疗 HD,特别是心力衰竭的发病率呈大幅上升趋势。

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