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短期远程缺血预处理与年轻成年人血压和运动能力的改善无关。

Short-term remote ischemic preconditioning is not associated with improved blood pressure and exercise capacity in young adults.

作者信息

Banks Laura, Wells Greg D, Clarizia Nadia A, Jean-St-Michel Emilie, McKillop Adam L, Redington Andrew N, McCrindle Brian W

机构信息

a Labatt Family Heart Centre, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada.

b Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, Canada.

出版信息

Appl Physiol Nutr Metab. 2016 Aug;41(8):903-6. doi: 10.1139/apnm-2016-0024. Epub 2016 Apr 18.

DOI:10.1139/apnm-2016-0024
PMID:27439445
Abstract

We sought to determine whether a 9-day remote ischemic preconditioning (IPC) causes improvements in exercise performance, energetics, and blood pressure. Ten participants (mean age 24 ± 4 years) had no changes in aerobic capacity (preintervention: 38 ± 10 mL/(kg·min)(-1) vs. postintervention: 38 ± 10 mL/(kg·min)(-1)), blood pressure (preintervention: 112 ± 7/66 ± 6 mm Hg vs. postintervention: 112 ± 10/62 ± 5 mm Hg), cardiac phosphocreatinine-to-adenosine-triphosphate ratio (preintervention: 2.1 ± 0.5 vs. postintervention: 2.3 ± 0.4), and postexercise skeletal muscle phosphocreatine recovery (preintervention: 34 ± 11 s vs. postintervention: 31 ± 11 s). Short-term remote IPC may be ineffective in improving these outcomes.

摘要

我们试图确定为期9天的远程缺血预处理(IPC)是否能改善运动表现、能量代谢和血压。10名参与者(平均年龄24±4岁)的有氧能力(干预前:38±10 mL/(kg·min)⁻¹ 对比干预后:38±10 mL/(kg·min)⁻¹)、血压(干预前:112±7/66±6 mmHg对比干预后:112±10/62±5 mmHg)、心肌磷酸肌酸与三磷酸腺苷的比值(干预前:2.1±0.5对比干预后:2.3±0.4)以及运动后骨骼肌磷酸肌酸恢复情况(干预前:34±11秒对比干预后:31±11秒)均无变化。短期远程IPC可能无法有效改善这些指标。

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