Diagnostic and Therapeutic Nuclear Medicine, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-Ku, Chiba, 263-8555, Japan.
Department of Nuclear Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
J Nucl Cardiol. 2018 Apr;25(2):635-651. doi: 10.1007/s12350-016-0591-3. Epub 2016 Jul 21.
With the increasing availability of positron emission tomography (PET) myocardial perfusion imaging, the absolute quantification of myocardial blood flow (MBF) has become popular in clinical settings. Quantitative MBF provides an important additional diagnostic or prognostic information over conventional visual assessment. The success of MBF quantification using PET/computed tomography (CT) has increased the demand for this quantitative diagnostic approach to be more accessible. In this regard, MBF quantification approaches have been developed using several other diagnostic imaging modalities including single-photon emission computed tomography, CT, and cardiac magnetic resonance. This review will address the clinical aspects of PET MBF quantification and the new approaches to MBF quantification.
随着正电子发射断层扫描（PET）心肌灌注成像的应用日益广泛，心肌血流（MBF）的绝对定量在临床环境中变得流行。与传统的视觉评估相比，定量 MBF 提供了重要的额外诊断或预后信息。使用正电子发射断层扫描/计算机断层扫描（CT）进行 MBF 定量的成功增加了对这种更易于获得的定量诊断方法的需求。在这方面，已经使用包括单光子发射计算机断层扫描、CT 和心脏磁共振在内的几种其他诊断成像方式开发了 MBF 定量方法。本综述将介绍 PET MBF 定量的临床方面和 MBF 定量的新方法。
