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积极看待:轻度阿尔茨海默病、血管性痴呆和混合性痴呆患者日常活动的主动性和表现得到保持。

Taking a positive spin: preserved initiative and performance of everyday activities across mild Alzheimer's, vascular and mixed dementia.

机构信息

School of Psychological Sciences, University of Manchester, Manchester, UK.

Personal Social Services Research Unit, University of Manchester, Manchester, UK.

出版信息

Int J Geriatr Psychiatry. 2017 Sep;32(9):959-967. doi: 10.1002/gps.4553. Epub 2016 Jul 22.

Abstract

OBJECTIVES

The literature commonly evaluates those daily activities which are impaired in dementia. However, in the mild stages, people with dementia (PwD) are still able to initiate and perform many of those tasks. With a lack of research exploring variations between different dementia diagnoses, this study sought to investigate those daily activities with modest impairments in the mild stages and how these compare between Alzheimer's disease (AD), vascular dementia (VaD) and mixed dementia.

METHODS

Staff from memory assessment services from nine National Health Service trusts across England identified and approached informal carers of people with mild dementia. Carers completed the newly revised Interview for Deteriorations in Daily Living Activities in Dementia 2 assessing the PwD's initiative and performance of instrumental activities of daily living (IADLs). Data were analysed using analysis of variance and Chi-square tests to compare the maintenance of IADL functioning across AD, VaD, and mixed dementia.

RESULTS

A total of 160 carers returned the Interview for Deteriorations in Daily Living Activities in Dementia 2, of which 109, 21, and 30 cared for someone with AD, VaD, and mixed dementia, respectively. There were significant variations across subtypes, with AD showing better preserved initiative and performance than VaD for several IADLs. Overall, PwD showed greater preservation of performance than initiative, with tasks such as preparing a hot drink and dressing being best maintained.

CONCLUSION

Findings can help classify dementia better into subtypes in order to receive bespoke support. It suggests that interventions should primarily address initiative to improve overall functioning. Copyright © 2016 John Wiley & Sons, Ltd.

摘要

目的

文献通常评估在痴呆症中受损的日常活动。然而,在轻度阶段,痴呆症患者(PwD)仍然能够发起和执行许多这些任务。由于缺乏研究探索不同痴呆症诊断之间的差异,本研究旨在调查轻度阶段中那些有适度障碍的日常活动,以及这些活动在阿尔茨海默病(AD)、血管性痴呆(VaD)和混合性痴呆之间的差异。

方法

来自英格兰九个国民保健服务信托的记忆评估服务的工作人员确定并联系了轻度痴呆症患者的非正式照顾者。照顾者完成了新修订的《痴呆症日常生活活动恶化访谈》,评估了 PwD 的主动性和工具性日常生活活动(IADL)的表现。使用方差分析和卡方检验来比较 AD、VaD 和混合性痴呆的 IADL 功能维持情况。

结果

共有 160 名照顾者返回了《痴呆症日常生活活动恶化访谈》,其中 109 名、21 名和 30 名分别照顾 AD、VaD 和混合性痴呆患者。亚型之间存在显著差异,AD 在几项 IADL 中表现出比 VaD 更好的主动性和表现。总体而言,PwD 的表现比主动性保持得更好,例如准备热饮和穿衣等任务保持得最好。

结论

研究结果可以帮助更好地将痴呆症分类为亚型,以获得定制化的支持。这表明干预措施应主要针对主动性,以提高整体功能。版权所有©2016 约翰威利父子有限公司。

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